ID A0A2K5MAV0_CERAT Unreviewed; 502 AA.
AC A0A2K5MAV0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=DEP domain containing 1B {ECO:0000313|Ensembl:ENSCATP00000022308.1};
GN Name=DEPDC1B {ECO:0000313|Ensembl:ENSCATP00000022308.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000022308.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000022308.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011889341.1; XM_012033951.1.
DR AlphaFoldDB; A0A2K5MAV0; -.
DR STRING; 9531.ENSCATP00000022308; -.
DR Ensembl; ENSCATT00000046515.1; ENSCATP00000022308.1; ENSCATG00000034781.1.
DR GeneID; 105573788; -.
DR KEGG; caty:105573788; -.
DR CTD; 55789; -.
DR GeneTree; ENSGT00950000182976; -.
DR OMA; THVNGKH; -.
DR OrthoDB; 5405142at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000034781; Expressed in bone marrow and 5 other cell types or tissues.
DR GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IEA:Ensembl.
DR CDD; cd04405; RhoGAP_BRCC3-like; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR16206; DEP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR16206:SF11; DEP DOMAIN-CONTAINING PROTEIN 1B; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00049; DEP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 1..81
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 174..366
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 502 AA; 58671 MW; 632B6ED0D43ADE7A CRC64;
MPLRKHRCRF KSYEHCFTAA EAVDWLHELL RCSQNFGPEV TRKQTVQLLK KFLKNHVIED
IKGKWGQEDF EDNRHLYRFP PSSPLKPYPK KPPYQKDVIK FPEWNDPAPG TSQENIPVRP
VVMNSEMWYK RHSIAIGEVP ACRLVHRRQL TEANVEEIWK SMTLSYLQKI LGLDSLEEIL
DIKLVNSKFI IHNVYSVSKQ GVVILDDKSK ELPHWVLSAM KCLANWPNCS DLKQPMYLGF
EKDVFKTIAD YYGHLKEPLL TFHLFDAFVS VLGLLQKEKV AVEAFQICCL LLPPENRRKL
QLLMRMMARI CLNKEMPPLC DGFGTRTLMV QTFSRCILCS KDEVDLDELL AARLVTFLMD
NYQEILKVPL DLQTSIEERV AHLRRVQIKY PGADMDITLS APSFCRQISP EEFEYQRSYG
SQEPLAALLE EVITDAKLSS KEKKKKLKQF QKSYPEVYQE RFPTPESEAL LFPEKPKPKP
QLLMWALKKP FQPFQRTRSF RM
//
