ID   A0A2K5ME51_CERAT        Unreviewed;       744 AA.
AC   A0A2K5ME51;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Heterogeneous nuclear ribonucleoprotein U {ECO:0000313|Ensembl:ENSCATP00000023485.1};
GN   Name=HNRNPU {ECO:0000313|Ensembl:ENSCATP00000023485.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000023485.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000023485.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A2K5ME51; -.
DR   Ensembl; ENSCATT00000047703.1; ENSCATP00000023485.1; ENSCATG00000035273.1.
DR   GeneTree; ENSGT00940000156546; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000035273; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR   CDD; cd12884; SPRY_hnRNP; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR035778; SPRY_hnRNP_U.
DR   PANTHER; PTHR12381:SF11; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U; 1.
DR   PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR   Pfam; PF13671; AAA_33; 1.
DR   Pfam; PF02037; SAP; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   SMART; SM00513; SAP; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50800; SAP; 1.
PE   4: Predicted;
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          8..42
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   DOMAIN          176..383
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          41..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          590..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          688..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..99
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..154
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..181
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        590..606
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   744 AA;  81841 MW;  8383BA03A22985A2 CRC64;
     MSSSPVNVKK LKVSELKEEL KKRRLSDKGL KAELMERLQA ALDDEEAGGR PAMEPGNGSL
     DLGGDSAGRS GAGLEQEAAV GGDEEEEEEE EEEEGISALD GDQMELGEEN GAAGAADSGP
     MEEEEAASED ENGDDQGFQE GEDELGDEEE GAGDENGHGE QQPQPPATQQ QQTQQQRGAA
     KEAAGKSSGP TSLFAVTVAP PGARQGQQQA GDNCDLHFKI SRDRLSASSL TMESFAFLWA
     GGRASYGVSK GKVCFEMKVT EKIPVRHLYT KDIDIHEVRI GWSLTTSGML LGEEEFSYGY
     SLKGIKTCNC ETEDYGEKFD ENDVITCFAN FESDEVELSY AKNGQDLGIA FKISKEVLAG
     RPLFPHVLCH NCAVEFNFGQ KEKPYFPIPE EYTFIQNVPL EDRVRGPKGP EEKKDCEVVM
     MIGLPGAGKT TWVTKHAAEN PGKYNILGTN TIMDKMMVAG FKKQMADTGK LNTLLQRAPQ
     CLGKFIEIAA RKKRNFILDQ TNVSAAAQRR KMCLFAGFQR KAVVVCPKDE DYKQRTQKKA
     EVEGKDLPEH AVLKMKGNFT LPEVAECFDE ITYVELQKEE AQKLLEQYKE ESKKALPPEK
     KQNTGSKKSN KNKSGKNQFN RGGGHRGRGG FNMRGGNFRG GAPGNRGGYN RRGNMPQRGG
     GGGGSGGIGY PYPRAPVFPG RGSYSNRGNY NRGGMPNRGN YNQNFRGRGN NRGYKNQSQG
     YNQWQQGQFW GQKPWSQHYH QGYY
//