ID A0A2K5MFJ1_CERAT Unreviewed; 396 AA.
AC A0A2K5MFJ1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Sorting nexin 7 {ECO:0000313|Ensembl:ENSCATP00000023972.1};
GN Name=SNX7 {ECO:0000313|Ensembl:ENSCATP00000023972.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000023972.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000023972.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Heterodimer; heterodimerizes with SNX4.
CC {ECO:0000256|ARBA:ARBA00038663}.
CC -!- SUBCELLULAR LOCATION: Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004469}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004469}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004469}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A2K5MFJ1; -.
DR Ensembl; ENSCATT00000048193.1; ENSCATP00000023972.1; ENSCATG00000035518.1.
DR GeneTree; ENSGT00940000155315; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000035518; Expressed in colon and 12 other cell types or tissues.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd06860; PX_SNX7_30_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR PANTHER; PTHR45949:SF3; SORTING NEXIN-7; 1.
DR Pfam; PF00787; PX; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 94..247
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 396 AA; 45100 MW; 63675937D9CE9602 CRC64;
MEGERRASQA RSSGLPAGGA DGESPGGSAP FPGSSGSSAL LQAEVLDLDE DEDDLEVFSK
DASLMDMNSF SPMMPTSPLS MINQIKFEDE PDLKDLFITV DEPESHVTTI ETFITYRIIT
KTSRGEFDSS EFEVRRRYQD FLWLKGKLEE AHPTLIIPEL SSHKKQGPGL LSRMGQTVRA
VASSMRGVKN RPEEFMEMNN FIELFSQKIN LIDKISQRIY KEEREYFDEM KEYGPIHILW
SASEEDLVDT LKDVAGCIDR CCKATEKRMS GLSEALLPVV HEYVLYSEML MGVMKRRDQI
QAELDSKVEA LTYKKTDTDL LPEEIGKLED KVECANNALK ADWERWKQNM QNDIKLAFTD
MAEENINYYE QCLATWESFL TSQTNLHLEE TSEDKP
//
