ID A0A2K5MHC2_CERAT Unreviewed; 557 AA.
AC A0A2K5MHC2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=PTPRF interacting protein alpha 1 {ECO:0000313|Ensembl:ENSCATP00000024608.1};
GN Name=PPFIA1 {ECO:0000313|Ensembl:ENSCATP00000024608.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000024608.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000024608.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR AlphaFoldDB; A0A2K5MHC2; -.
DR Ensembl; ENSCATT00000048834.1; ENSCATP00000024608.1; ENSCATG00000035769.1.
DR GeneTree; ENSGT01050000244900; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000035769; Expressed in colon and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF15; LIPRIN-ALPHA-1; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 250..316
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 342..399
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 423..492
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 62111 MW; 7B9BBD716E0CABE5 CRC64;
MSSIPPYPAS SLASSSPPGS GRSTPRRIPH SPAREVDRLG VMTLPSPDSF LIQTSGPHQS
VVYSSTSPPS SIPCYSDSSQ HAQPSDLRKH RRKLPPSREE VRDDKTTIKC ETSPPSSPRA
LRLDRLHKGA LHTVSHEDIR DLRNSTGSQD GPVSNPSSSN SSQDSLHKAP KKKGIKSSIG
RLFGKKEKGR PGQTGKEALG QAGVSETDNS SQDALGLSKL GGQAEKNRKL QKKHELLEEA
RRQGLPFAQW DGPTVVVWLE LWVGMPAWYV AACRANVKSG AIMSALSDTE IQREIGISNP
LHRLKLRLAI QEIMSLTSPS APPTSRTTLA YGDMNHEWIG NEWLPSLGLP QYRSYFMECL
VDARMLDHLT KKDLRGQLKM VDSFHRNSFQ CGIMCLRRLN YDRKELERKR EESQSEIKDV
LVWSNDRVIR WILSIGLKEY ANNLIESGVH GALLALDETF DFSALALLLQ IPTQNTQARA
VLEREFNNLL VMGTDRRFDE DDDKSFRRAP SWRKKFRPKD IRGLAAGSAE TLPANFRVTS
SMSSPSMQPK KMQMDGM
//
