ID A0A2K5MK01_CERAT Unreviewed; 422 AA.
AC A0A2K5MK01;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=TRIM5alpha {ECO:0000256|ARBA:ARBA00032496};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000025536.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000025536.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K5MK01; -.
DR STRING; 9531.ENSCATP00000025536; -.
DR Ensembl; ENSCATT00000049766.1; ENSCATP00000025536.1; ENSCATG00000036232.1.
DR GeneTree; ENSGT00940000163213; -.
DR OMA; FHFNFAF; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000036232; Expressed in cerebellum and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19783; Bbox2_TRIM43-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF637; TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 15..56
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 70..111
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 239..422
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 422 AA; 49546 MW; 351BA409535C7363 CRC64;
MSSGILQVFQ RELTCPICMN YFIDPVTTDC GHSFCRPCFY LNWQDIPLLV QCSECRKSTR
KASLWQFLSS EEQMCGTHRE TKKMFCEVDR SLLCLLCSSS QKHRDHKHCP IEWAAEEHRE
KLLKKMQSLW EEACENHRNL NMETTRTKYW KDYVNLRLEA VRVEYQKMPA LHHEEEKHNL
EMLKKKGKDI FHQLHLSKAK MELKKMCHKP DVELLQGFGD ILHRSESVLL HKPQPLNLEL
SSGPIAGLMD RLNQFRVHIT LHQEEANSHI FRYEILRSMC IGCDHQDVPY ITATPRSFLA
WGAQTFTSGK YYWEFHVEDS WNWAFGVCNT YWKEKNQNEK IDGEEGLFLL GCVKNDIQCH
LFTTSPLMLQ YISRPTSRVG LFLDYEAKTV SFVDVNQSSL IYTIPNCSFS PPLRPVFCCI
HF
//
