ID A0A2K5MLW9_CERAT Unreviewed; 401 AA.
AC A0A2K5MLW9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Arylacetamide deacetylase like 2 {ECO:0000313|Ensembl:ENSCATP00000026233.1};
GN Name=AADACL2 {ECO:0000313|Ensembl:ENSCATP00000026233.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000026233.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000026233.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 'GDXG' lipolytic enzyme family.
CC {ECO:0000256|ARBA:ARBA00010515}.
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DR RefSeq; XP_011941410.1; XM_012086020.1.
DR AlphaFoldDB; A0A2K5MLW9; -.
DR STRING; 9531.ENSCATP00000026233; -.
DR Ensembl; ENSCATT00000050469.1; ENSCATP00000026233.1; ENSCATG00000036536.1.
DR GeneID; 105597608; -.
DR KEGG; caty:105597608; -.
DR CTD; 344752; -.
DR GeneTree; ENSGT00940000161405; -.
DR OMA; DHVYTEP; -.
DR OrthoDB; 1144477at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR InterPro; IPR017157; Arylacetamide_deacetylase.
DR InterPro; IPR033140; Lipase_GDXG_put_SER_AS.
DR PANTHER; PTHR23024; ARYLACETAMIDE DEACETYLASE; 1.
DR PANTHER; PTHR23024:SF223; ARYLACETAMIDE DEACETYLASE-LIKE 2; 1.
DR Pfam; PF07859; Abhydrolase_3; 2.
DR PIRSF; PIRSF037251; Arylacetamide_deacetylase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS01174; LIPASE_GDXG_SER; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..401
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014459713"
FT DOMAIN 107..257
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT DOMAIN 311..373
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT ACT_SITE 189
FT /evidence="ECO:0000256|PIRSR:PIRSR037251-1,
FT ECO:0000256|PROSITE-ProRule:PRU10038"
FT ACT_SITE 341
FT /evidence="ECO:0000256|PIRSR:PIRSR037251-1"
FT ACT_SITE 371
FT /evidence="ECO:0000256|PIRSR:PIRSR037251-1"
SQ SEQUENCE 401 AA; 46032 MW; F6ABB026FE19D216 CRC64;
MMLKALCLGL LCVIFVSHFY TPMPDNIEES WKIMALDAIA KTCTFTAMCF ENMGIMRYEE
FISMIFKLDY TQPLSDEYIT VTDTTFVDIP VRLYLPKRKS EIRRRAVIYF HGGGFCFGSS
KQRAFDFLNR WTANTLDAVV VGVDYRLAPQ HHFPAQFEDG LAAVKFFLLE KILTKYGVDP
TRICISGDSS GGNLATAVTQ QVQNDAEIKH KIKMQVLLYP GLQITDSYLP SHRENEHGIV
LTRDVAIKLV SLYFTKDEAL PRAMRRNQHM PLESRHLFKF VNWSILLPEK YRKDYVYTEP
ILGGLSYSLP GLTDSRALPL LANDSQLQNL PLTYILTCQH DVLRDDGLMY VTRLRNVGVQ
VVHDHIEDGI HGALSYMTSP FYLRLGLRIR DMYVSWLDKN L
//
