ID   A0A2K5MS81_CERAT        Unreviewed;      1255 AA.
AC   A0A2K5MS81;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=TBC1 domain family member 9B {ECO:0000313|Ensembl:ENSCATP00000028076.1};
GN   Name=TBC1D9B {ECO:0000313|Ensembl:ENSCATP00000028076.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000028076.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000028076.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011925347.1; XM_012069957.1.
DR   AlphaFoldDB; A0A2K5MS81; -.
DR   STRING; 9531.ENSCATP00000028076; -.
DR   Ensembl; ENSCATT00000052327.1; ENSCATP00000028076.1; ENSCATG00000037328.1.
DR   GeneID; 105590412; -.
DR   KEGG; caty:105590412; -.
DR   CTD; 23061; -.
DR   GeneTree; ENSGT00940000158554; -.
DR   OrthoDB; 3034081at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000037328; Expressed in thymus and 12 other cell types or tissues.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd13351; PH-GRAM1_TCB1D9_TCB1D9B; 1.
DR   CDD; cd13354; PH-GRAM2_TCB1D9_TCB1D9B; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   InterPro; IPR036014; TCB1D9/TCB1D9B_PH-GRAM1.
DR   InterPro; IPR036017; TCB1D9/TCB1D9B_PH-GRAM2.
DR   PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR47666:SF3; TBC1 DOMAIN FAMILY MEMBER 9B; 1.
DR   Pfam; PF02893; GRAM; 2.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00054; EFh; 1.
DR   SMART; SM00568; GRAM; 2.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          509..696
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   DOMAIN          887..915
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          397..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          975..1005
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1074..1162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        984..1005
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1074..1096
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1134..1148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1255 AA;  141030 MW;  A618CF778FF67DB1 CRC64;
     MWLSPEEVLV ANALWVTERA NPFFVLQRRR GHGKGGGLTG LLVGTLDVVL DSSARVAPYR
     ILHQTQDSQV YWTVACGSSR KEITKHWEWL ENNLLQTLSI FDSEEDITTF VKGKIHGIIA
     EENKNLQPQG DEDPGKFKEA ELKMRKQFGM PEGEKLVNYY SCSYWKGRVP RQGWLYLTIN
     HLCFYSFLLG KEVSLVVQWV DITRLEKNAT LLFPESIRVD TRDQELFFSM FLNIGETFKL
     MEQLANLAMR QLLDSEGFLE DRVLPRPVRP HRNISALKRD LDARAKNECY RATFRLPRDE
     RLDGHTSCTL WTPFNKLHIP GQMFISNNYI CFASKEEDAC HLIIPLREVT IVEKADSSSV
     LPSPLSISTK SKMTFLFANL KDRDFLVQRI SDFLQKTPSK QPGSIVGSRK ASVVDTNTES
     SPAPQEVPEQ PASPASPLSS RQSFCAQEVP TASQGLLKLF QKNSPMEDLG AKGAKEKMKE
     ESWHIHFFEY GRGVCMYRTA KTRALVLKGI PESLRGELWL LFSGAWNEMV THPGYYAELV
     EKSTGKYSLA TEEIERDLHR SMPEHPAFQN ELGIAALRRV LTAYAFRNPT IGYCQAMNIV
     TSVLLLYGSE EEAFWLLVAL CERMLPDYYN TRVVGALVDQ GIFEELTRDF LPQLSEKMQD
     LGVISSISLS WFLTLFLSVM PFESAVVIVD CFFYEGIKVI LQVALAVLDA NMEQLLGCSD
     EGEAMTMLGR YLDNVVNKQS VSPPIPHLHA LLTSGDDPPA EVDIFELLKV SYEKFSSLRA
     EDIEQMRFKQ RLKVIQSLED TAKRSVVRAI PVDIGFSIEE LEDLYMVFKA KHLASQYWGS
     SHTVAGRRDP SLPYLEQYRI DASQFRELFA SLTPWACGSH TPVLAGRMFR LLDKNKDSLI
     NFKEFVTGMS GMYHGDLTEK LKVLYKLHLP PALSPEEAES ALEAAHYFTE DSSSEASPLA
     SDLDLFLPWE AQEALPQEEQ EGSGGEDVQE KRGEEKGTSS PDYRHYLRMW AKEKEAQKET
     IKDLPKMNQE QFIELCKTLY NMFSEDPMEQ DLYHAIATVA SLLLRIGEVG KKFSARTGRK
     PRDCATEEDE PPAPGPHQDA ARELQPPAAG DPQAKAGGDT HLGKAPQESQ VVVEGGSGEG
     QGSPSQLLSD DETKDDMSMS SYSVVSTGSL QCEDLTDDTV LVGGEACSPT ARIGGTVDTD
     WCISFEQILA SILTESVLVN FFEKRVDIGL KIKDQKKVER QFSTASDHEQ PGASS
//