ID   A0A2K5MTT3_CERAT        Unreviewed;      1315 AA.
AC   A0A2K5MTT3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=FA complementation group I {ECO:0000313|Ensembl:ENSCATP00000028495.1};
GN   Name=FANCI {ECO:0000313|Ensembl:ENSCATP00000028495.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000028495.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000028495.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSCATT00000052750.1; ENSCATP00000028495.1; ENSCATG00000037507.1.
DR   GeneTree; ENSGT00390000005855; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000037507; Expressed in bone marrow and 12 other cell types or tissues.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd11720; FANCI; 1.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029310; FANCI_HD1.
DR   InterPro; IPR029312; FANCI_HD2.
DR   InterPro; IPR029308; FANCI_S1.
DR   InterPro; IPR029305; FANCI_S1-cap.
DR   InterPro; IPR029315; FANCI_S2.
DR   InterPro; IPR029313; FANCI_S3.
DR   InterPro; IPR029314; FANCI_S4.
DR   PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR   PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR   Pfam; PF14679; FANCI_HD1; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
DR   Pfam; PF14675; FANCI_S1; 1.
DR   Pfam; PF14674; FANCI_S1-cap; 1.
DR   Pfam; PF14676; FANCI_S2; 1.
DR   Pfam; PF14677; FANCI_S3; 1.
DR   Pfam; PF14678; FANCI_S4; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          1..53
FT                   /note="FANCI solenoid 1 cap"
FT                   /evidence="ECO:0000259|Pfam:PF14674"
FT   DOMAIN          64..266
FT                   /note="FANCI solenoid 1"
FT                   /evidence="ECO:0000259|Pfam:PF14675"
FT   DOMAIN          270..357
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14679"
FT   DOMAIN          365..528
FT                   /note="FANCI solenoid 2"
FT                   /evidence="ECO:0000259|Pfam:PF14676"
FT   DOMAIN          542..772
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14680"
FT   DOMAIN          791..1019
FT                   /note="FANCI solenoid 3"
FT                   /evidence="ECO:0000259|Pfam:PF14677"
FT   DOMAIN          1032..1281
FT                   /note="FANCI solenoid 4"
FT                   /evidence="ECO:0000259|Pfam:PF14678"
FT   REGION          1287..1315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1315 AA;  147926 MW;  41942D40FAB84228 CRC64;
     MDQKILSLAA EKTADKLQEF LQTLREDDLT NLLQNQAVKG KVAGALLRAI FKGSPCCEEA
     GALRRRKIYA YCIQLVESGD LQKEIASEII GLLMLEAHHF PGPLLVELAN EFISAVREGS
     LVNGKSLELL PIILTALATK KENLAYGKGV LSGEECKKQL INILCSGRDV PLTAEEVEFV
     VEKALSMFSK MNLQEIPPLV YQLLVLSSKG SRKSVLEGII AFFSALDKQH NEEQTGDELL
     DVVTVPSGEL RHVEGTIILH IVFAIKLDYE LGRELLKHLK VAGQQGDSNN NLSPFSIALL
     LSVTRIQRFQ DQVLDLLKTS VVKSFKDLQL LQGSKFLQNL VPHRSYVSTM ILEVVKNSVH
     SWDHVTQGLV ELGFILMDSY GPKKVLDGKT IETSPSLSRM PNQHACKLGA NILLETFKIH
     EMIRQEILEQ VLNRVVTRAS SPISHFLDLL SNIVMYAPLV LQSCSSKVTE AFDYLSFLPL
     QTVQRLLKAV QPLLKVSMSM RDSLILVLRK AMFANQLDAR KSAVAGFLLL LKNFKVLGSL
     SSSQCSQSLS FSQVHVDVHS HYNSVANETF CLEIMDSLRR CLSQQADVRL MLYEGFYDVL
     RRNSQLANSI MQTLLSQLKQ FYEPKPDLLP PLKLEACILT QGDKISLQEP LDYLLCCIQH
     CLAWYKNTVI PLQQGEEEEE EEEAFYQALD DILESITNRM IKSELEDFEL DKSADFSQST
     SIGIKNNICA FLVMGVCEVL IEYNFSISNF SKNKFEDILS LFMCYKKLSD ILNEKAGKAK
     TKMANKTNDS LLSMKFVSSL LTVLFRDSIQ SHQESLSVLR SSSEFMRYAV NIALQKVQQL
     KETGHVSGPD GQNPDKIFQN LCDITRVLLW RYTSIPTSVE ESGKKEKGKS ISLLCLEGLQ
     KIFSAVQQFY QPKIQQFLRA LDVTDKEGEE REDADVSVTQ RTAFQIRQFQ RSLLNLLSSQ
     EEDFNSKEAL LLVTVLTSLS KLLEPSSPQF VQMLSWTSKI CKENSREDAL FCKSLMNLLF
     SLHVLYKSPV ILLRDLSQDI HGHLGDIDQD VEVEKTNHFA IVNLRTAAPT ICLLVLSQAE
     KVLEEVDWLI TKLKGQVSQE TVSEEASSQT TLPNQPVEKA IVMQLGTLLT FFHELVQTAL
     PSGSCVDTLL KDLCKMYTTL TALVRYYLQV CQSSGGIPKN MEKLVKLSGS HLTPVCYSFI
     SYVQNKSKSL NYTGEKKEKP ATVATAMARV LRETKPIPNL IFAIEQYEKF LIHLSKRSKV
     NLMQHMKLST SRDFKIKGNI LDMVLREDGE DENEEGTASE HGEQNKEPAK KKRKK
//