ID   A0A2K5N3I3_CERAT        Unreviewed;       593 AA.
AC   A0A2K5N3I3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Keratin, type II cytoskeletal 5 {ECO:0000256|ARBA:ARBA00039423};
DE   AltName: Full=Cytokeratin-5 {ECO:0000256|ARBA:ARBA00042962};
DE   AltName: Full=Keratin-5 {ECO:0000256|ARBA:ARBA00042885};
DE   AltName: Full=Type-II keratin Kb5 {ECO:0000256|ARBA:ARBA00043132};
GN   Name=KRT5 {ECO:0000313|Ensembl:ENSCATP00000032052.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000032052.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000032052.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   RefSeq; XP_011903568.1; XM_012048178.1.
DR   AlphaFoldDB; A0A2K5N3I3; -.
DR   STRING; 9531.ENSCATP00000032052; -.
DR   Ensembl; ENSCATT00000056319.1; ENSCATP00000032052.1; ENSCATG00000039121.1.
DR   GeneID; 105580306; -.
DR   KEGG; caty:105580306; -.
DR   CTD; 3852; -.
DR   GeneTree; ENSGT00940000160458; -.
DR   OrthoDB; 4640531at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000039121; Expressed in thymus and 3 other cell types or tissues.
DR   GO; GO:0005829; C:cytosol; IEA:UniProt.
DR   GO; GO:0045095; C:keratin filament; IEA:Ensembl.
DR   GO; GO:0097110; F:scaffold protein binding; IEA:Ensembl.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR032444; Keratin_2_head.
DR   InterPro; IPR003054; Keratin_II.
DR   PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45616:SF32; KERATIN, TYPE II CYTOSKELETAL 5; 1.
DR   Pfam; PF00038; Filament; 1.
DR   Pfam; PF16208; Keratin_2_head; 1.
DR   PRINTS; PR01276; TYPE2KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          167..480
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          569..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          236..298
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          378..465
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        570..593
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   593 AA;  62599 MW;  239FDF5F1A1CBC62 CRC64;
     MSRQSSVSFR SGGSRSFSTA SAITPSVSRT SFTSVSRSGG GGGGFGRVSL GGACGVGGYG
     SRSLYNLGGS KRISISTSGG SFRNRFGAGA GGGYGFGGGA GSGFGFGGGA GGGFGLGGGA
     GFGGGFGGPG FPVCPPGGIQ EVTVNQSLLT PLNLQIDPSI QRVRTEEREQ IKTLNNKFAS
     FIDKVRFLEQ QNKVLDTKWT LLQEQGTKTV RQNLEPLFEQ YINNLRRQLD SIVGERGRLD
     SELRNMQDLV EDFKNKYEDE INKRTTAENE FVMLKKDVDA AYMNKVELEA RVDALMDEIN
     FMKMFFDAEL SQMQTHVSDT SVVLSMDNNR NLDLDSIIAE VKAQYEEIAN RSRTEAESWY
     QTKYEELQQT AGRHGDDLRN TKHEISEMNR MIQRLRAEID NVKKQCANLQ NAIADAEQRG
     ELALKDARHK LAELEEALQK AKQDMARLLR EYQELMNTKL ALDVEIATYR KLLEGEECRL
     SGEGVGPVNI SVVTSSVSSG YGGGSGYGGG LGGGLGGGLG GGLGGGLSGG GSGSYYSSSS
     GGVGLGGGLS VGGSGFSASS GRGLGVGFGS GGGSSSSVKF VSTTSSSRKS FKS
//