ID   A0A2K5N3T8_CERAT        Unreviewed;       977 AA.
AC   A0A2K5N3T8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Formin like 3 {ECO:0000313|Ensembl:ENSCATP00000032168.1};
GN   Name=FMNL3 {ECO:0000313|Ensembl:ENSCATP00000032168.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000032168.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000032168.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the formin homology family.
CC       {ECO:0000256|ARBA:ARBA00023449}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_011903769.1; XM_012048379.1.
DR   AlphaFoldDB; A0A2K5N3T8; -.
DR   Ensembl; ENSCATT00000056435.1; ENSCATP00000032168.1; ENSCATG00000039154.1.
DR   GeneID; 105580375; -.
DR   CTD; 91010; -.
DR   GeneTree; ENSGT00940000159962; -.
DR   OMA; ELANFWH; -.
DR   OrthoDB; 471257at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000039154; Expressed in lung and 12 other cell types or tissues.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR010472; FH3_dom.
DR   InterPro; IPR043592; FMNL_animal.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   InterPro; IPR010473; GTPase-bd.
DR   PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR   PANTHER; PTHR45857:SF3; FORMIN-LIKE PROTEIN 3; 1.
DR   Pfam; PF06367; Drf_FH3; 1.
DR   Pfam; PF06371; Drf_GBD; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM01139; Drf_FH3; 1.
DR   SMART; SM01140; Drf_GBD; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          26..421
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          510..900
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          442..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          340..413
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          874..903
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        461..490
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   977 AA;  111478 MW;  D6F748328F095EE6 CRC64;
     MGNLESAEGG PGEPPSVPLL LPPGKMPMPE PCELEERFAL VLSSMNLPPD KARLLRQYDN
     EKKWDLICDQ ERFQVKNPPH TYIQKLQSFL DPSVTRKKFR RRVQESTKVL RELEISLRTN
     HIGWVREFLN DENKGLDVLV DYLSFAQCSV MYSTLPGRRA LKNSRLVSQK DDVHVCILCL
     RAIMNYQYGF NLVMSHPHAV NEIALSLNNK NPRTKALVLE LLAAVCLVRG GHEIILAAFD
     NFKEVCKELH RFEKLMEYFR NEDSNIDFMV ACMQFINIVV HSVEDMNFRV HLQYEFTKLG
     LEEFLQKSRH TESEKLQVQI QAYLDNVFDV GGLLEDAETK NVALEKVEEL EEHVSHLTEK
     LLDLENENMM RVAELEKQLL QREKELESIK ETYENTSHQV HTLRRLIKEK EEAFQRRCHL
     EPSVRGLESV GSEALARVGP AELSEGMPPS NLDLLAPATP PEEVLPLPPP PAPPLPPPPP
     PLPDKCPPAP PLPGAAPSVV LTVGLSAIRI KKPIKTKFRL PVFNWTALKP NQISGTVFSE
     LDDEKILEDL DLDKFEELFK TKAQGPALDL ICSKNKTAQK AASKVTLLEA NRAKNLAITL
     RKAGRSAEEI CRAIHTFDLQ TLPVDFVECL MRFLPTEAEV KLLRQYERER QPLEELAAED
     RFMLLFSKVE RLTQRMAGMA FLGNFQDNLQ MLTPQLNAII AASASVKSSQ KLKQMLEIIL
     ALGNYMNSSK RGAVYGFKLQ SLDLLLDTKS TDRKMTLLHF IALTVKEKYP DLANFWHELH
     FVEKAAAVSL ENVLLDVKEL GRGMELIRRE CSIHDNSVLR NFLSTNEGKL DKLQRDAKTA
     EEAYNAVVRY FGESPKTTPP SVFFPVFVRF IRSYKEAEQE NEARKKQEEV MREKQLAQEA
     KKLDAKTPSQ RNKWQQQELI AELRRRQAKE HRPVYEGKDG TIEDIITVLK SVPFTARTAK
     RGSRFFCDAA HHDESNC
//