ID   A0A2K5N4L4_CERAT        Unreviewed;       996 AA.
AC   A0A2K5N4L4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Ankyrin 3 {ECO:0000313|Ensembl:ENSCATP00000032270.1};
GN   Name=ANK3 {ECO:0000313|Ensembl:ENSCATP00000032270.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000032270.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000032270.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
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DR   AlphaFoldDB; A0A2K5N4L4; -.
DR   Ensembl; ENSCATT00000056537.1; ENSCATP00000032270.1; ENSCATG00000039015.1.
DR   GeneTree; ENSGT00940000154939; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000039015; Expressed in cerebellum and 12 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd08803; Death_ank3; 1.
DR   Gene3D; 2.60.220.30; -; 2.
DR   Gene3D; 2.60.40.2660; -; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR037971; Ank3_Death.
DR   InterPro; IPR040745; Ankyrin_UPA.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR000906; ZU5_dom.
DR   PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24198:SF173; ANKYRIN-3; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF17809; UPA_2; 1.
DR   Pfam; PF00791; ZU5; 1.
DR   SMART; SM00005; DEATH; 1.
DR   SMART; SM00218; ZU5; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51145; ZU5; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          118..273
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          275..422
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          611..695
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          758..799
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          886..917
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          944..996
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        758..772
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        957..985
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   996 AA;  110645 MW;  BA705318EBB3A4B1 CRC64;
     LSTSAGEDAM TGDTDKYLGP QDLKELGDDS LPAEGYMGFS LGARSASLRS FSSDRSYTLN
     RSSYARDSMM IEELLVPSKE QHLTFTREFD SDSLRHYSWA ADTLDNVNLV SSPIHSGFLV
     SFMVDARGGS MRGSRHHGMR IIIPPRKCTA PTRITCRLVK RHKLANPPPM VEGEGLASRL
     VEMGPAGAQF LGPVIVEIPH FGSMRGKERE LIVLRSENGE TWKEHQFDSK NEDLTELLNG
     MDEELDSPEE LGKKRICRII TKDFPQYFAV VSRIKQESNQ IGPEGGILSS TTVPLVQASF
     PEGALTKRIR VGLQAQPVPD EIVKKILGNK ATFSPIVTVE PRRRKFHKPI TMTIPVPPPS
     GEGVSNGYKG DSTPNLRLLC SITGGTSPAQ WEDITGTTPL TFIKDCVSFT TNVSARFWLA
     DCHQVLETVG LATQLYRELI CVPYMAKFVV FAKMNDPVES SLRCFCMTDD KVDKTLEQQE
     NFEEVARSKD IEVLEGKPIY VDCYGNLAPL TKGGQQLVFN FYAFKENRLP FSIKIRDTSQ
     EPCGRLSFLK EPKTTKGLPQ TAVCNLNITL PAHKKIEKTD RRQSFASLAL RKRYSYLTEP
     GMSPQSPCER TDIRMAIVAD HLGLSWTELA RELNFSVDEI NQIRVENPNS LISQSFMLLK
     KWVTRDGKNA TTDALTSVLT KINRIDIVTL LEGPIFDYGN ISGTRSFADE NNVFHDPVDG
     YPSLQVELET PTGLHYTPPT PFQQDDYFSD ISSIESPLRT PSRLSDGLVP SQGNIEHSAD
     GPPVVTAEDT SLEDSKLEDS VPLTEMPEAV DVDESQLENV CLILKTFVSE TYIQAYVAIV
     NLQIFLCSPD QCRDSITSYL KGEAGKFEAN GSHTEITPEA KTKSYFPESQ NDVGKQSTKE
     TLKPKIHGSG HVEEPASPLA AYQKSLEETS KFVIEETKPC VPVSMKKMSR TSPADGKPRL
     NLHEEEGSSG SEQKQGEGFK VKTKKEIRHV EKKSHS
//