ID A0A2K5N5Q9_CERAT Unreviewed; 602 AA.
AC A0A2K5N5Q9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=X-ray repair cross complementing 1 {ECO:0000313|Ensembl:ENSCATP00000032833.1};
GN Name=XRCC1 {ECO:0000313|Ensembl:ENSCATP00000032833.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000032833.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000032833.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K5N5Q9; -.
DR Ensembl; ENSCATT00000057104.1; ENSCATP00000032833.1; ENSCATG00000039431.1.
DR GeneTree; ENSGT00390000004140; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000039431; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0000012; P:single strand break repair; IEA:InterPro.
DR CDD; cd17725; BRCT_XRCC1_rpt1; 1.
DR CDD; cd17707; BRCT_XRCC1_rpt2; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR045080; BRCT_XRCC1_rpt1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002706; Xrcc1_N.
DR PANTHER; PTHR11370:SF6; DNA REPAIR PROTEIN XRCC1; 1.
DR PANTHER; PTHR11370; DNA-REPAIR PROTEIN XRCC1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF01834; XRCC1_N; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50172; BRCT; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 284..372
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 507..598
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 190..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..254
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..400
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..455
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..497
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 66188 MW; 248C1E622D1A0DBF CRC64;
MPEIRLRHVV SCSSQDSLEK EEQIHSVDIG NDGSAFVEVL VGSSAGGAGE QDYEVLLVTS
SFMSPSESRS GSNPHRVRMF GPDKLVRAAA EKRWDRVKIV CSQPYSKDSP FGLSFVRFHS
PPDKDEAEAP SQKVTVTKLG QFRVKEEDES ANSLRPGALF FSRINKTSPV TASDPAGPSY
AAATLQASSA ASSASPVSRA IGSTSKPQES PKGKRKLDLN QEEKKTPSKP PAQLSPSVPK
RPKLPAPTRT PAAVPVPAPA QGAVTGKPRG EGTEPRRPRA GPEELGKILQ GVVVVLSGFQ
NPFRSELRDK ALELGAKYRP DWTQDSTHLI CAFANTPKYS QVLGLGGRIV RKEWVLDCHR
MRRRLPSRRY LMAGPGSSSE EDEASHSGSS GDEAPKLPRK RPQTKTKPTQ ATGPSLPQKP
PSPEETKAAS PVLQEDIDIE GEQSEGQDNG AEDSGDTEDE LRRVAEQKEH RPPPVQEENG
EDPYAGSTDE NTDDEEHQEP PDLPVPELPD FFQGKHFFLY GEFPGDERRK LIRYVTAFNG
ELEDYMSDRV QFVITAQEWD PSFEEALMDN PSLAFVRPRW IYSCNEKQKL LPHQLYGVVP
QA
//
