ID A0A2K5N675_CERAT Unreviewed; 595 AA.
AC A0A2K5N675;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=X-ray repair cross complementing 1 {ECO:0000313|Ensembl:ENSCATP00000032835.1};
GN Name=XRCC1 {ECO:0000313|Ensembl:ENSCATP00000032835.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000032835.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000032835.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K5N675; -.
DR Ensembl; ENSCATT00000057106.1; ENSCATP00000032835.1; ENSCATG00000039431.1.
DR GeneTree; ENSGT00390000004140; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000039431; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0000012; P:single strand break repair; IEA:InterPro.
DR CDD; cd17725; BRCT_XRCC1_rpt1; 1.
DR CDD; cd17707; BRCT_XRCC1_rpt2; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR045080; BRCT_XRCC1_rpt1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002706; Xrcc1_N.
DR PANTHER; PTHR11370:SF6; DNA REPAIR PROTEIN XRCC1; 1.
DR PANTHER; PTHR11370; DNA-REPAIR PROTEIN XRCC1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF01834; XRCC1_N; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50172; BRCT; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 277..365
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 500..591
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 183..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..247
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..448
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..490
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 595 AA; 65292 MW; B38AE34004FC4A8F CRC64;
AIIGFSLCPQ LEKEEQIHSV DIGNDGSAFV EVLVGSSAGG AGEQDYEVLL VTSSFMSPSE
SRSGSNPHRV RMFGPDKLVR AAAEKRWDRV KIVCSQPYSK DSPFGLSFVR FHSPPDKDEA
EAPSQKVTVT KLGQFRVKEE DESANSLRPG ALFFSRINKT SPVTASDPAG PSYAAATLQA
SSAASSASPV SRAIGSTSKP QESPKGKRKL DLNQEEKKTP SKPPAQLSPS VPKRPKLPAP
TRTPAAVPVP APAQGAVTGK PRGEGTEPRR PRAGPEELGK ILQGVVVVLS GFQNPFRSEL
RDKALELGAK YRPDWTQDST HLICAFANTP KYSQVLGLGG RIVRKEWVLD CHRMRRRLPS
RRYLMAGPGS SSEEDEASHS GSSGDEAPKL PRKRPQTKTK PTQATGPSLP QKPPSPEETK
AASPVLQEDI DIEGEQSEGQ DNGAEDSGDT EDELRRVAEQ KEHRPPPVQE ENGEDPYAGS
TDENTDDEEH QEPPDLPVPE LPDFFQGKHF FLYGEFPGDE RRKLIRYVTA FNGELEDYMS
DRVQFVITAQ EWDPSFEEAL MDNPSLAFVR PRWIYSCNEK QKLLPHQLYG VVPQA
//
