ID   A0A2K5N9H6_CERAT        Unreviewed;       302 AA.
AC   A0A2K5N9H6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE            EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN   Name=SULT6B1 {ECO:0000313|Ensembl:ENSCATP00000034142.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000034142.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000034142.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3'-phosphoadenylyl sulfate + thyroxine = adenosine 3',5'-
CC         bisphosphate + H(+) + thyroxine sulfate; Xref=Rhea:RHEA:26422,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58339, ChEBI:CHEBI:58343,
CC         ChEBI:CHEBI:58910, ChEBI:CHEBI:305790; EC=2.8.2.n2;
CC         Evidence={ECO:0000256|ARBA:ARBA00036007};
CC   -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC       {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR   AlphaFoldDB; A0A2K5N9H6; -.
DR   STRING; 9531.ENSCATP00000034142; -.
DR   Ensembl; ENSCATT00000058418.1; ENSCATP00000034142.1; ENSCATG00000040009.1.
DR   GeneTree; ENSGT00940000159084; -.
DR   OMA; VCSAETF; -.
DR   Proteomes; UP000233060; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR11783:SF341; SULFOTRANSFERASE 6B1; 1.
DR   PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT   DOMAIN          56..289
FT                   /note="Sulfotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00685"
SQ   SEQUENCE   302 AA;  34829 MW;  33F357A6173E7534 CRC64;
     MADKSKFIEY IDEALEKSKE TALSRLFFTY QGIPYPITMC TSETFQALDT FEARHDDIVL
     ASYPKCGSNW ILHIVHELIF AVSKKKYEYP EFPVLECGDS EKYQRMKGFP SPRILATHLH
     YDKLPGSIFK NKAKILVIFR NPKDTAVSFF HFHNDVPDIP SYCSWDEFFR QFMKGQVSWG
     SYFDFAINWN KHLDGDNVKF ILYEDLKENL AAGIKQIADF LGFFLTGEQI QTISVQSTFQ
     AMRAKSQDTH GAVGPFLFRK GEVGDWKNLF SETQNQEMDE KFKECLAGTS LGAKLKYESY
     CG
//