ID   A0A2K5NAR2_CERAT        Unreviewed;       813 AA.
AC   A0A2K5NAR2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=MALT1 paracaspase {ECO:0000313|Ensembl:ENSCATP00000034577.1};
GN   Name=MALT1 {ECO:0000313|Ensembl:ENSCATP00000034577.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000034577.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000034577.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011924423.1; XM_012069033.1.
DR   AlphaFoldDB; A0A2K5NAR2; -.
DR   Ensembl; ENSCATT00000058857.1; ENSCATP00000034577.1; ENSCATG00000040183.1.
DR   GeneID; 105589974; -.
DR   CTD; 10892; -.
DR   GeneTree; ENSGT00390000018044; -.
DR   OrthoDB; 3080800at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000040183; Expressed in lymph node and 12 other cell types or tissues.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd08783; Death_MALT1; 1.
DR   CDD; cd00096; Ig; 1.
DR   Gene3D; 2.60.40.3360; -; 1.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR037940; MALT1_Death.
DR   InterPro; IPR041077; MALT1_Ig.
DR   InterPro; IPR033540; MALT1_IG-like_dom_sf.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   InterPro; IPR001309; Pept_C14_p20.
DR   PANTHER; PTHR22576; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE; 1.
DR   PANTHER; PTHR22576:SF40; MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1; 1.
DR   Pfam; PF13927; Ig_3; 2.
DR   Pfam; PF18703; MALT1_Ig; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   SMART; SM00409; IG; 2.
DR   SMART; SM00408; IGc2; 2.
DR   SUPFAM; SSF52129; Caspase-like; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 2.
DR   PROSITE; PS50208; CASPASE_P20; 1.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          125..201
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          212..307
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          330..408
FT                   /note="Caspase family p20"
FT                   /evidence="ECO:0000259|PROSITE:PS50208"
SQ   SEQUENCE   813 AA;  91089 MW;  BD44256C0DF43282 CRC64;
     MSLLGDPLQA LPPSAALTGP LLAPPAGATL NRLREPLLRR LSEHLDQAPE GRGWRRLAEL
     AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ
     LLSPPGIKIT INPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV
     HVKDAGFYVC RVNNNVTFEF SQWSQLDVCD VPESFRRSVD GVSESKLQIC VEPTSQKLMP
     GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD
     SKKAEIIIDE LNNLGHPDNK EQTTDQPLAK DKVALLIGNM NYREHPKLKA PLVDVYELTN
     LLRQLDFKVV SLLDLTEYEM RNAVDEFLLL LDKGVYGLLY YAGHGYENFG NSFMVPVDAP
     NPYRSENCLC VQNILKLMQE KETGLNVFLL DMCRKRNDYD DTIPILDALK VTANIVFGYA
     TCQGAEAFEI QHSGLANGIF MKFLKDRLLE DKKITVLLDE VAEDMGKCHL TKGKQALEIR
     SSLSEKRALT DPIQGTEYSA ESLVRNLQWA KAHELPESMC LKFDCGVQIQ LGFAAEFSNV
     MIIYTSIVYK PPEIIMCDAY VTDFPLDLDI DPKDANKGTP EETGSYLVSK DLPKHCLYTR
     LSSLQKLKEH LVFTVCLSYQ YSGLEDTVED KQEVNVGKPL IAKLDMHRGL GRKTCFQTCL
     MSNGPYQSSA ATSGGAGHYH SLQDPFHGVY HSHPGNPSNV TPADSCHCSR TPDAFISSFA
     HHSSCHFSRS NVPVETTDEI PFSFSDRLRI SEK
//