ID A0A2K5NBQ2_CERAT Unreviewed; 811 AA.
AC A0A2K5NBQ2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=LON peptidase N-terminal domain and ring finger 3 {ECO:0000313|Ensembl:ENSCATP00000034922.1};
GN Name=LONRF3 {ECO:0000313|Ensembl:ENSCATP00000034922.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000034922.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000034922.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011942994.1; XM_012087604.1.
DR AlphaFoldDB; A0A2K5NBQ2; -.
DR STRING; 9531.ENSCATP00000034922; -.
DR Ensembl; ENSCATT00000059203.1; ENSCATP00000034922.1; ENSCATG00000040361.1.
DR GeneID; 105598395; -.
DR KEGG; caty:105598395; -.
DR CTD; 79836; -.
DR GeneTree; ENSGT00440000033329; -.
DR OMA; RLMPHWS; -.
DR OrthoDB; 3088759at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000040361; Expressed in lung and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16513; RING-HC_LONFs_rpt1; 1.
DR CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327:SF41; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3; 1.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00464; LON; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51787; LON_N; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS00518; ZF_RING_1; 2.
DR PROSITE; PS50089; ZF_RING_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 158..195
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 243..276
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 519..557
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 605..805
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 90318 MW; F1A50E6DFAAD7BA3 CRC64;
MESLRTEQML SLPAEVSSNN LEPAERGASA AQVDMGPHRE AAAESPAPLP TREPEQEQSP
GTSTPESKVL LTQADALASR GRIREALEVY RQLSERQQLV AEQLEQLVRC LAEKVPQGEV
LAPAPPGEGS TASGAVAAEE IGAAAAAAAT EVWDGFKCRK CHGFLSDPVS LSCGHTFCKL
CLERGRAADR RCALCGVKLS ALMVATGRAR GSRRAGQQPP PPLRVNVVLS GLLGKLFPGP
ARASQLRHEG NRLYRERQVE AALLKYNEAV KLAPNDHLLY SNRSQIYFTL ESHENALHDA
EIACKLRPMG FKAHFRKAQA LATLGKVEEA LREFLYCVSL DGKNKRARCE AQRLLLSFFS
PSVPGDSQEH SPDILKLLAP HPRLKENVES MTTEVTSHNL PRWLQDNLEL PHCSSQEEAA
ARGDGSSLMD PAKVKGDGQQ HHIKDQEEEE EKWDATSPKA ASSKTGKCQE KKRKHCQIES
QEDTGMPNKA SKQDPPTDQG DKPALSLPLA SFDASDLECA LCMRLFYEPV TTPCGHTFCL
KCLERCLDHN AKCPLCKDGL SQCLASRKYG KNVIMEELIA KFLPEELKER RKLYEEEMEE
LSNLNKNVPI FVCTMAYPTV PCPLHIFEPC YRLMIRRCIE TGTRQFGMCL GDPVKGFAEY
GCILEIRNVQ FFADGRSVVD SIGKRRFRVL HQSQRDGYNT ADIEYIEDQK VQGEDCAELM
GLHNCVYQQA SLWFHSLKSS LKNRILNHFG PMPEKDADPQ MNPNGPAWCW WMLAVLPLES
RAQLPFLAMR SLKDRLNGIR RVLAFISRNQ N
//
