ID A0A2K5NCQ2_CERAT Unreviewed; 322 AA.
AC A0A2K5NCQ2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=D-aspartate oxidase {ECO:0000313|Ensembl:ENSCATP00000035267.1};
GN Name=DDO {ECO:0000313|Ensembl:ENSCATP00000035267.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000035267.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000035267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000189-1};
CC -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
CC -!- SIMILARITY: Belongs to the DAMOX/DASOX family.
CC {ECO:0000256|ARBA:ARBA00006730}.
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DR RefSeq; XP_011905885.1; XM_012050495.1.
DR AlphaFoldDB; A0A2K5NCQ2; -.
DR Ensembl; ENSCATT00000059549.1; ENSCATP00000035267.1; ENSCATG00000040509.1.
DR GeneID; 105581364; -.
DR CTD; 8528; -.
DR GeneTree; ENSGT00390000018635; -.
DR OrthoDB; 5359at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000040509; Expressed in heart and 4 other cell types or tissues.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0003884; F:D-amino-acid oxidase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0019478; P:D-amino acid catabolic process; IEA:UniProt.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006181; D-amino_acid_oxidase_CS.
DR InterPro; IPR023209; DAO.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR PANTHER; PTHR11530; D-AMINO ACID OXIDASE; 1.
DR PANTHER; PTHR11530:SF11; D-ASPARTATE OXIDASE; 1.
DR Pfam; PF01266; DAO; 1.
DR PIRSF; PIRSF000189; D-aa_oxidase; 2.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR PROSITE; PS00677; DAO; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000189-1};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000189-1};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 119..305
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT BINDING 83..84
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
FT BINDING 204
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
FT BINDING 259
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
SQ SEQUENCE 322 AA; 35077 MW; A247810FF4D4A813 CRC64;
MGSSFAFPLS QGTRPARHCK TSFGARDFGG FQDCFFRDRP MDTARIAVVG AGVVGLSTAV
CISKLVPQCS VTIISDKFTP DTTSDVAAGM LIPHTYPDTP IHMQKQWFRE TFNHLFAIAN
SAEAGDAGVH LVSGIKGSGG WMLTRRIDDL WELYPSFDIV VNCSGLGSRQ LAGDSKIFPV
RGQVLQVQAP WVEHFIRDGS GLTYIYPGTS HVTLGGTRQK GDWNLSPDAE NSREILSRCC
ALEPSLHGAC NIREKVGLRP YRPGVRLQTE LLARDGRRLP VVHHYGHGSG GISVHWGTAL
EAARLVSECV HALRTPIPKS KL
//
