ID   A0A2K5NIE0_CERAT        Unreviewed;       255 AA.
AC   A0A2K5NIE0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=DNA replication complex GINS protein PSF3 {ECO:0000256|RuleBase:RU367161};
GN   Name=GINS3 {ECO:0000313|Ensembl:ENSCATP00000037197.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000037197.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000037197.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000256|RuleBase:RU367161}.
CC   -!- SUBUNIT: Component of the GINS complex.
CC       {ECO:0000256|RuleBase:RU367161}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU367161}.
CC   -!- SIMILARITY: Belongs to the GINS3/PSF3 family.
CC       {ECO:0000256|ARBA:ARBA00006343, ECO:0000256|RuleBase:RU367161}.
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DR   AlphaFoldDB; A0A2K5NIE0; -.
DR   STRING; 9531.ENSCATP00000037197; -.
DR   Ensembl; ENSCATT00000061494.1; ENSCATP00000037197.1; ENSCATG00000041344.1.
DR   GeneTree; ENSGT00390000001622; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000041344; Expressed in bone marrow and 9 other cell types or tissues.
DR   GO; GO:0071162; C:CMG complex; IEA:Ensembl.
DR   GO; GO:0000811; C:GINS complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR   CDD; cd11713; GINS_A_psf3; 1.
DR   CDD; cd21693; GINS_B_Psf3; 1.
DR   Gene3D; 1.20.58.2050; -; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR010492; GINS_Psf3.
DR   InterPro; IPR038437; GINS_Psf3_sf.
DR   PANTHER; PTHR22768:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF3; 1.
DR   PANTHER; PTHR22768; UNCHARACTERIZED; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR   SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|RuleBase:RU367161};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367161};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          106..212
FT                   /note="GINS subunit"
FT                   /evidence="ECO:0000259|Pfam:PF05916"
SQ   SEQUENCE   255 AA;  28662 MW;  0A28FA8F77F0079D CRC64;
     MSEAYFRVES GALGPEENFL SLDDILMSHE KLPVRTETAM PRLGAFFLER SAGAETDNAV
     PQGLALLPRV ECSGVIWLTA ALTSQAQVIV IPQPPMWLGL QGSKLELPLW LAKGLFDNKR
     RILSVELPKI YQEGWRTVFS ADANVVDLHK MGPHFYGFGS QLLHFDSPEN ADISQSLLQT
     FIGRFRRIMD SSQNAYNEDT SALVARLDEM ERGLFQTGQK GLNDFQCWEK GQASQITASN
     LVQNYKKRKF TDMED
//