ID A0A2K5NJG3_CERAT Unreviewed; 927 AA.
AC A0A2K5NJG3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Spliceosome associated factor 3, U4/U6 recycling protein {ECO:0000313|Ensembl:ENSCATP00000037669.1};
GN Name=SART3 {ECO:0000313|Ensembl:ENSCATP00000037669.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000037669.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000037669.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5NJG3; -.
DR Ensembl; ENSCATT00000061967.1; ENSCATP00000037669.1; ENSCATG00000041537.1.
DR GeneTree; ENSGT00900000141107; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000041537; Expressed in cerebellum and 12 other cell types or tissues.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd12391; RRM1_SART3; 1.
DR CDD; cd12392; RRM2_SART3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR008669; LSM_interact.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034217; SART3_RRM1.
DR InterPro; IPR034218; SART3_RRM2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR15481; RIBONUCLEIC ACID BINDING PROTEIN S1; 1.
DR PANTHER; PTHR15481:SF5; SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNIZED BY T-CELLS 3; 1.
DR Pfam; PF16605; LSM_int_assoc; 1.
DR Pfam; PF05391; Lsm_interact; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00386; HAT; 6.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 668..746
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 765..842
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..912
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..569
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..658
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 927 AA; 105447 MW; BEAA8062948F3B7A CRC64;
MATAAATSAS EPEAESKAGP KADGEEDEVK AARTRRKVLS RAVAAATYKT VGPGWDQQEE
GVSESDGDEY AMASSAESSP GEYEWEYDEE EEKNQLEIER LEEQLSINVY DYNCHVDLIR
LLRLEGELTK VRMARQKMSE IFPLTEELWL EWLHDEISMA QDGLDREHVY DLFEKAVKDY
ICPNIWLEYG QYSVGGIGQK GGLEKVRSVF ERALSSVGLH MTKGLALWEA YREFESAIVE
AARLEKVHSL FRRQLAIPLY DMEATFAEYE EWSEDPVPES VIQNYNKALQ QLEKYKPYEE
ALLQAEAPRL SEYQAYIDFE MKIGDPARVQ LIFERALVEN CLVPDLWIRY SQYLDRQLKV
KDLVLSVHNR AVRNCPWTVA LWSRYLLAME RHGVDHQVIS DSSKELEELR AAFTRALEYL
KQEVEERFNE SGDPSCVIMQ NWARIEARLC NNMQKARELW DSIMTRGNAK YANMWLEYYN
LERAHGDTQH CRKALHRAVQ CTSDYPEHVC EVLLTMERTE GSLEDWDTAV QKTETRLARV
NEQRMKAAEK EAALVQQEEE KAEQRKRARA EKKALKKKKK TRGPEKRGAD EDDEKEWGDD
EEEQPSKRRR VENSIPAAGE TQNIEVAAGP AGKCATVDVE PPSKQKEKAA SLKRDMPKVL
HDSSKDSITV FVSNLPYSMQ EPDVKLRPLF EACGEVVQIR PIFSNRGDFR GYCYVEFKEE
KSALQALEMD RKSVEGRPMF VSPCVDKSKN PDFKVFRYST SLEKHKLFIS GLPFSCTKEE
LEEICKAHGT VKDLRLVTNR AGKPKGLAYV EYENESQASQ AVMKMDGMTI KENVIKVAIS
NPPQRKVPEK PETRKAPGGP MLLPQTYGAR GKGRTQLSLL PRALQRPSAA APQAENGPAA
APAVAASAAT EAPKMSNADF AKLFLRK
//
