ID A0A2K5NLD4_CERAT Unreviewed; 367 AA.
AC A0A2K5NLD4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=tRNA (cytosine(38)-C(5))-methyltransferase {ECO:0000256|ARBA:ARBA00039681};
DE EC=2.1.1.204 {ECO:0000256|ARBA:ARBA00039081};
DE AltName: Full=DNA (cytosine-5)-methyltransferase-like protein 2 {ECO:0000256|ARBA:ARBA00042810};
GN Name=TRDMT1 {ECO:0000313|Ensembl:ENSCATP00000038339.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000038339.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000038339.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
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DR AlphaFoldDB; A0A2K5NLD4; -.
DR Ensembl; ENSCATT00000062644.1; ENSCATP00000038339.1; ENSCATG00000041864.1.
DR GeneTree; ENSGT00390000016416; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000041864; Expressed in adult mammalian kidney and 12 other cell types or tissues.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR031303; C5_meth_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR46098; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR46098:SF1; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF00145; DNA_methylase; 2.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00095; C5_MTASE_2; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 79
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 367 AA; 41910 MW; 3458C62167F16148 CRC64;
MEPLRVLELY SGVGGMHHAL RESCIPAQVV AAIDVNTVAN EVYKYNFPHT QLLAKTIEGV
TLEEFDRLSF DMILMSPPCQ PFTRLQKLPK YILLENVKGF EVSSTRDLFI QTIENCGFQY
QEFLLSPTSL GIPNSRLRYF LIAKLQSEPL PFQAPGQVLM QFPKIESVHP QKDTMDVENK
IQEKNIEPNI SFDSSTQCSG KDAILFKLET AEEIHRKNQQ DSDLSVKMLK DFLEDDTDMN
QYLLPPKSLL RYALLLDIVQ PTCRRSVCFT KGYGSYIEGT GSVLQTAEDV QIENIYKSLT
KLSQEEQITK LLMLKLRYFT PKEIANLLGF PPEFGFPEKI TVKQRYRLLG NSLNVHVVAK
LIKILCE
//
