ID A0A2K5NN38_CERAT Unreviewed; 723 AA.
AC A0A2K5NN38;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Vacuolar protein sorting-associated protein 52 homolog {ECO:0000256|ARBA:ARBA00017083};
GN Name=VPS52 {ECO:0000313|Ensembl:ENSCATP00000038785.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000038785.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000038785.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the VPS52 family.
CC {ECO:0000256|ARBA:ARBA00008180}.
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DR RefSeq; XP_011932016.1; XM_012076626.1.
DR AlphaFoldDB; A0A2K5NN38; -.
DR STRING; 9531.ENSCATP00000038785; -.
DR Ensembl; ENSCATT00000063092.1; ENSCATP00000038785.1; ENSCATG00000042050.1.
DR GeneID; 105593463; -.
DR CTD; 6293; -.
DR GeneTree; ENSGT00390000008815; -.
DR OMA; IHVVMVE; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000042050; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:1990745; C:EARP complex; IEA:Ensembl.
DR GO; GO:0000938; C:GARP complex; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0019905; F:syntaxin binding; IEA:Ensembl.
DR GO; GO:0010668; P:ectodermal cell differentiation; IEA:Ensembl.
DR GO; GO:0048611; P:embryonic ectodermal digestive tract development; IEA:Ensembl.
DR GO; GO:0032456; P:endocytic recycling; IEA:Ensembl.
DR GO; GO:0007041; P:lysosomal transport; IEA:Ensembl.
DR GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0090119; P:vesicle-mediated cholesterol transport; IEA:Ensembl.
DR InterPro; IPR007258; Vps52.
DR InterPro; IPR048361; Vps52_C.
DR InterPro; IPR048319; Vps52_CC.
DR PANTHER; PTHR14190; SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52; 1.
DR PANTHER; PTHR14190:SF7; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG; 1.
DR Pfam; PF20655; Vps52_C; 1.
DR Pfam; PF04129; Vps52_CC; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 101..273
FT /note="Vps52 coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF04129"
FT DOMAIN 290..601
FT /note="Vps52 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20655"
SQ SEQUENCE 723 AA; 82215 MW; 4B5CE220C206FD67 CRC64;
MAAAATMAAA ARELVLRAGT SDMEEEEGPL AGGAGLQESL QLGELDITSD EFILDEVDVH
IQANLEDELV KEALKTGVDL RHYSKQVELE LQQIEQKSIR DYIQESENIA SLHNQITACD
AVLERMEQML GAFQSDLSSI SSEIRTLQEQ SGAMNIRLRN RQAVRGKLGE LVDGLVVPSA
LVTAILEAPV TEPRFLEQLQ ELDAKAAAVR EQEARGTAAC ADVRGVLDRL RVKAVMKIRE
FILQKIYSFR KPMTNYQIPQ TALLKYRFFY QFLLGNERAT AKEIRDEYVE TLSKIYLSYY
RSYLGRLMKV QYEEVAEKDD LMGVEDTAKK GFFSKPSLRS RNTIFTLGTR GSVISPTELE
APILVPHTAQ RGEQRYPFEA LFRSQHYALL DNSCREYLFI CEFFVVSGPA AHDLFHAVMG
RTLSMTLKHL ESYLADCYDA IAVFLCIHIV LRFRNIAAKR DVPALDRYWE QVLALLWPRF
ELILEMNVQS VRSTDPQRLG GLDTRPHYIT RRYAEFSSAL VSINQTIPNE RTMQLLGQLQ
VEVENFVLRV AAEFSSRKEQ LVFLINNYDM MLGVLMERAA DDSKEVESFQ QLLNARTQEF
IEELLSPPFG GLVAFVKEAE ALIERGQAER LRGEEARVTQ LIRGFGSSWK SSVESLSQDV
MRSFTNFRNG TSIIQGALTQ LIQVYHRFHR VLSQPQLRAL PARAELINIH HLMVELKKHK
PNF
//
