ID A0A2K5NNV8_CERAT Unreviewed; 319 AA.
AC A0A2K5NNV8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=F-box protein 8 {ECO:0000313|Ensembl:ENSCATP00000039050.1};
GN Name=FBXO8 {ECO:0000313|Ensembl:ENSCATP00000039050.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000039050.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000039050.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011941752.1; XM_012086362.1.
DR SMR; A0A2K5NNV8; -.
DR STRING; 9531.ENSCATP00000039050; -.
DR Ensembl; ENSCATT00000063357.1; ENSCATP00000039048.1; ENSCATG00000042187.1.
DR Ensembl; ENSCATT00000063359.1; ENSCATP00000039050.1; ENSCATG00000042187.1.
DR GeneID; 105597792; -.
DR KEGG; caty:105597792; -.
DR CTD; 26269; -.
DR GeneTree; ENSGT00940000158356; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000042187; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd22088; F-box_FBXO8; 1.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR048003; FBXO8_F-box.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 68..111
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 133..314
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
SQ SEQUENCE 319 AA; 37081 MW; 2A10274D3E3FC424 CRC64;
MGQGLWRVVR NQQLQQEGYS EQGYLTREQS RRMAANNISN SNHRKQVQGG IDIYHLLKAR
KSKEQEGFIN LEMLPPELSF TILSYLNATD LCLASCVWQD LANDELLWQG LCKSTWGHCS
IYNKNPPLGF SFRKLYMQLD EGSLTFNANP DEGVNYFMSK GILDDSPKEI AKFIFCTRTL
NWKKLRIYLD ERRDVLDDLV TLHNFRNQFL PNALREFFRH IHAPEERGEY LETLITKFSH
RFCACNPDLM RELGLSPDAV YVLCYSLILL SIDLTSPHVK NKMSKREFIR NTRRAAQNIS
EDFVGHLYDN IYLIGHVAA
//
