ID   A0A2K5NQK9_CERAT        Unreviewed;       464 AA.
AC   A0A2K5NQK9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Ras and Rab interactor 2 {ECO:0000313|Ensembl:ENSCATP00000039819.1};
GN   Name=RIN2 {ECO:0000313|Ensembl:ENSCATP00000039819.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000039819.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000039819.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5NQK9; -.
DR   Ensembl; ENSCATT00000064132.1; ENSCATP00000039819.1; ENSCATG00000042503.1.
DR   GeneTree; ENSGT00940000154866; -.
DR   OMA; CRDANTE; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000042503; Expressed in colon and 12 other cell types or tissues.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd16131; RA_Rin2; 1.
DR   Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR003123; VPS9.
DR   InterPro; IPR045046; Vps9-like.
DR   InterPro; IPR037191; VPS9_dom_sf.
DR   PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR23101:SF51; RAS AND RAB INTERACTOR 2; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF02204; VPS9; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00167; VPS9; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   SUPFAM; SSF109993; VPS9 domain; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS51205; VPS9; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          187..326
FT                   /note="VPS9"
FT                   /evidence="ECO:0000259|PROSITE:PS51205"
FT   DOMAIN          356..447
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   REGION          29..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  53533 MW;  B739C543B53D069D CRC64;
     MSISTSSSDS LEFDRSMPLF GYEADTNSSL EDYEGESDQE TMAPPIKSKK KRSSSFVLPK
     LVKSQLQKVS GVFSSFMTPE KRMVRRIAEL SRDKCTYFGC LVQDYVSFLQ ENKECHVSST
     DMLQTIRQFM TQVKNYLSQS SELDPPIESL IPEDQIDVVL EKAMHKCILK PLKGHVEAML
     KDFHMADGSW KQLKENLQLV RQRNPQELGV FAPTPDFVDV EKIKVKFMTM QKMYSPEKKV
     MLLLRVCKLI YTVMENNSGR MYGADDFLPV LTYVIAQCDM LELDTEIEYM MELLDPSLLH
     GEGGYYLTSA YGALSLIKNF QEEQAARLLS SETRDTLRQW HKRRTTNRTI PSVDDFQNYL
     RVAFQEVNSG CTGKTLLVRP YITTEDVCQI CAEKFKVGDP EEYSLFLFVD ETWQQLAEDT
     YPQKIKAELH SRPQPHIFHF VYKRIKNDPY GVIFQNGEDD LTTS
//