ID A0A2K5NRK2_CERAT Unreviewed; 583 AA.
AC A0A2K5NRK2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Zinc finger protein 721 {ECO:0000313|Ensembl:ENSCATP00000040010.1};
GN Name=ZNF721 {ECO:0000313|Ensembl:ENSCATP00000040010.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000040010.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000040010.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K5NRK2; -.
DR Ensembl; ENSCATT00000064324.1; ENSCATP00000040010.1; ENSCATG00000042570.1.
DR GeneTree; ENSGT01100000263534; -.
DR OMA; CNAHVKV; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000042570; Expressed in cerebellum and 12 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 14.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24393:SF62; ZINC FINGER PROTEIN 680; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 10.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 4..74
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 193..220
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 248..275
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 276..303
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 304..331
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 332..359
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 360..387
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 388..415
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 416..443
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 444..471
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 472..499
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 500..527
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 528..555
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 556..583
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 583 AA; 67656 MW; E69BF7F49A27A427 CRC64;
MEHLTFRDVA IEFSPEEWKC LDPAQQNLYR DVMLENYRNL VSLGVAISNP DLVTFLQRKE
PYNVKIHETV AKHPAMCSHF TQDFLPVQEI EDSFHKLILR RYEKCGHENL QLRKGCKKKV
QKAGYNEFSQ CLSTTQSKIF QCNAHVIVFS KFSNSNQHKT RHTGEKHFKE CGKSSQKFSD
LTHKGIHAGE KPYTCEECGK DFKWYLVFNE YKVIHTGEKP FICEQCGNIF TTFSNFAKRK
VHTEEKSFKY EECGKAFNRS STLTKHKRIH AEEKPFTCEE CGKIITSSSN VAKHKKIHTR
EKLYKCQECG KAFNRSTTLT KHKRIHTGEK PYTCEECGKA FSRSSVLNEH KRIHTGEKPY
KCEQCGKAFR QSATLNKHNR IHTGEKPYPC EECGKAFSRF TTLNEHKRIH TGEKPHKCEE
CGKAFIWSTD LNKHKIIHTG EKPYKCEECG KAFGWSAYLS KHKKIHTGEK PYKCEECGKA
FICSRALNKH KTIHTGDKPY KCEECGKAFG WSTYLSKHKK IHTGQKLYKC EECGKAFRRS
RVLNKRKIIH TGDKTPKCKG CGKAFKRPLY LNQHNKIFTG EKL
//
