ID A0A2K5NZR1_CERAT Unreviewed; 1031 AA.
AC A0A2K5NZR1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=KIAA0319 {ECO:0000313|Ensembl:ENSCATP00000042861.1};
GN Name=KIAA0319 {ECO:0000313|Ensembl:ENSCATP00000042861.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000042861.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000042861.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_011886842.1; XM_012031452.1.
DR RefSeq; XP_011886843.1; XM_012031453.1.
DR RefSeq; XP_011886844.1; XM_012031454.1.
DR RefSeq; XP_011886845.1; XM_012031455.1.
DR RefSeq; XP_011886846.1; XM_012031456.1.
DR RefSeq; XP_011886847.1; XM_012031457.1.
DR RefSeq; XP_011886854.1; XM_012031464.1.
DR Ensembl; ENSCATT00000067294.1; ENSCATP00000042858.1; ENSCATG00000044020.1.
DR Ensembl; ENSCATT00000067297.1; ENSCATP00000042861.1; ENSCATG00000044020.1.
DR GeneID; 105572620; -.
DR KEGG; caty:105572620; -.
DR CTD; 9856; -.
DR GeneTree; ENSGT00940000161462; -.
DR OMA; HPVDYQG; -.
DR OrthoDB; 3021035at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000044020; Expressed in cerebellum and 4 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029865; KIAA0319-like.
DR InterPro; IPR013980; MANSC_dom.
DR InterPro; IPR011106; MANSC_N.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR46182:SF1; DYSLEXIA-ASSOCIATED PROTEIN KIAA0319; 1.
DR PANTHER; PTHR46182; FI19480P1; 1.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00765; MANEC; 1.
DR SMART; SM00089; PKD; 4.
DR SUPFAM; SSF49299; PKD domain; 4.
DR PROSITE; PS50986; MANSC; 1.
DR PROSITE; PS50093; PKD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1031
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014295238"
FT TRANSMEM 915..940
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..99
FT /note="MANSC"
FT /evidence="ECO:0000259|PROSITE:PS50986"
FT DOMAIN 545..618
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 168..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1005..1031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1031 AA; 112735 MW; 78BFF452451EBF5C CRC64;
MAPPTGVLSS LLLLVTVAGC ACKQCSEGRT YSNAVISPNL ETTRIMRVSH TFPVVDCTAA
CCDLSSCDLA WWFEGHCYLV SCPHKENCEP KKMGPIRSYL TFVLRPVQRP AQLLDYGDMM
LNRGSPSGIW GESPEDIRKD LPFLGKDWGL GEMSEYSDDY RELEKDLLQP NGKQEPRGSA
EYMDWGLLPG SEGGFNSSVG DSPEVPAETQ QDPELHYLNE SASTPAPKLP ERSVLLPLPT
TPSSGELLEK EKASQLQEQS SNSSGKEVLM PSHSLPPASL ELSSATVKKS PVLTVTLGST
EHSIPTPPTS TASSGSTPSE LPISPTTAPR TVKELMVSAG DNLIITLPDN EVELKAFVVP
APPAETTYSY EWSLISHPID YQGEIKQGHL QTLNLSQLSV GLYVFKVAVS SENAFGEGFV
NVTVKPARRA NLPPVAVVSP QLQELTLPLT SALIDGSQST DDTEIVSYHW EEINGPFIEE
KTSVDSPVLR LSNLDPGNYS FRLTVTDSDG ATNSTTAALI VNNAMDYPPV ANAGPNHTIT
LPQNSITLNG NQSSDDHQIV LYEWSLGPGS EGKHVAMQGV QTPYLHLSAM QEGDYTFQLK
VTDSSRQQST AVVTVIVQPE NNRPPVAVAG PDKELIFPVE SATLDGSSSS DDHGIVFYHW
EHIRGPSAVE MENIDKAIAT VTGLQVGTYR FRLTVKDQQG LSSTSTLTVA VKKENNSPPR
ARAGGRHVLV LPNNSVTLDG SRSTDDQGIV SYLWIRDGQS PAAGDVIDGS DHSAALQLMN
LVEGVYTFHL RVTDSQGASD TDTATVEVQP DPRRSGLVEL TLQVGVGQLT EQRKDTLVRQ
LAVLLNVLDS DIKVQKIRAH SDLSTVIVFY VQSGPPFKVL KAAEVARNLH TRLSKEKADF
LLFKVLRVDT AEWSIFYVTV LGFTLTVLTG GFTWLCICCY KRQKRTKIRK KTKYTILDNM
DEQERMELRP KYGIKHRSTE HNSSLMVSES EFDSDQDTIF SREKMERGNP KVSMNGSIRN
GASFSYCSKD R
//
