ID   A0A2K5P111_CERAT        Unreviewed;       478 AA.
AC   A0A2K5P111;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Melanophilin {ECO:0000313|Ensembl:ENSCATP00000043428.1};
GN   Name=MLPH {ECO:0000313|Ensembl:ENSCATP00000043428.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000043428.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000043428.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K5P111; -.
DR   Ensembl; ENSCATT00000067867.1; ENSCATP00000043428.1; ENSCATG00000044238.1.
DR   GeneTree; ENSGT00950000183138; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000044238; Expressed in lung and 2 other cell types or tissues.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   CDD; cd15752; FYVE_SlaC2-a; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR041282; FYVE_2.
DR   InterPro; IPR037442; Melanophilin_FYVE-rel_dom.
DR   InterPro; IPR010911; Rab_BD.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR14555:SF1; MELANOPHILIN; 1.
DR   PANTHER; PTHR14555; MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED; 1.
DR   Pfam; PF02318; FYVE_2; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50916; RABBD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          4..124
FT                   /note="RabBD"
FT                   /evidence="ECO:0000259|PROSITE:PS50916"
FT   REGION          143..212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          379..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..323
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..348
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        432..447
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        448..462
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   478 AA;  52382 MW;  D66E96DF73E571B9 CRC64;
     MGKKLDLSKL TDEEAQHILE VVQRDFDLRR KEEERLEGLK GKIKKESSKR ELLSDTAHLN
     ETRCTHCLQP YRLLVNSKRQ CLECGRFTCK SCGRVHPEEQ GWICDPCHLA RVVKIGSLEW
     YYEHVRARFK RFGSAKVIRS LHGRLQGGAG PESISEERSG DSEQTDEEGE LDSEAQAQPF
     GNKSLTDESC SEKAAPQKAE GLDGADTGAS GCQHHIEEEP MSVSPSGHGA LAELCPPGGS
     HSMALGAAAA LRSNVIRNEQ LPLQYLADVD TSDEESIRAH VMASHHSKRR GRASSESQGL
     GAGVRTEADV EEETLRKKLE ELTSNVSDQG TSSEEEEAKD EKAEPDRGKS VGAVPQADPE
     VSDIESRIAA LRAAGLTVKP SGKPRRKSNL PIFLPRVAGK LGKRPEDPNA DPSSEAKAMA
     APYLLRRKFS NSLKNQGKDD DSFDRKSVYR GSLTQRNPNG RKGMASHTFA KPVVAHQP
//