ID A0A2K5P3Q4_CERAT Unreviewed; 1252 AA.
AC A0A2K5P3Q4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=PTPRF interacting protein alpha 4 {ECO:0000313|Ensembl:ENSCATP00000044339.1};
GN Name=PPFIA4 {ECO:0000313|Ensembl:ENSCATP00000044339.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000044339.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000044339.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR AlphaFoldDB; A0A2K5P3Q4; -.
DR STRING; 9531.ENSCATP00000044339; -.
DR Ensembl; ENSCATT00000068780.1; ENSCATP00000044339.1; ENSCATG00000044625.1.
DR GeneTree; ENSGT01050000244900; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000044625; Expressed in cerebellum and 10 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0098688; C:parallel fiber to Purkinje cell synapse; IEA:Ensembl.
DR GO; GO:0098793; C:presynapse; IEA:Ensembl.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF5; LIPRIN-ALPHA-4; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 831..897
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 954..1011
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1035..1104
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 534..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1153..1194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 30..121
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 165..192
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 228..412
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 445..472
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 639..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1252 AA; 140308 MW; 20384EAD2EA38E36 CRC64;
MCEVMPTINE GDPLGPPHGA DADANFEQLM VNMLDEREKL LESLRESQET LAATQSRLQD
ALHERDQLQR HLNSALPQEF ATLTRELSMC REQLLEREEE ISELKAERNN TRLLLEHLEC
LVSRHERSLR MTVVKRQAQS PSGVSSEVEV LKALKSLFEH HKALDEKVRE RLRAALERVT
TLEEQLAGAH QQVSALQQGA GVLDGAAEEE GTVELGPKRL WKEDAGRVEE LQELLEKQNF
ELSQARERLV TLTATVTELE EDLGTARRDL IKSEELSSKH QRDLREALAQ KEDMEERITT
LEKRYLAAQR EATSIHDLND KLENELANKE SLHRQCEEKA RHLQELLEVA EQKLQQTMRK
AETLPEVEAE LAQRIAALTK AEERHGNIEE HLRQLEGQLE EKNQELARVR QREKMNEDHN
KRLSDTVDRL LSESNERLQL HLKERMAALE EKGRLSEEIE KLRQEVDQLK GRGGPFVDGV
HSRSHMGSAA DVRFSLGTTT HAPPGVHRRY SALREESAKD WETSPLPGML APAAAPAFDS
DPEISDADED EPGGLVGSAD VVSPSGHSDA QTLAMMLQEQ LDAINEEIRM IQEEKESTEL
RAEEIETRVT SGSMEALNLK QLRKRGSIPT SLTALSLASA SPPLSGRSTP KLTSRSAAQD
LDRMGVMTLP SDLRKHRRKL LSPVSREENR EDKATIKCET SPPSSPRTLR LEKLGHPALS
QEEGKSALED QGSNPSSSNS SSQDSLHKGA KRKGIKSSIG RLFGKKEKGR LIQLSRDGAT
GHVLLTDSEF SMQEPMVPAK LGTQAEKDRR LKKKHQLLED ARRKGMPFAQ WDGPTVVSWL
ELWVGMPAWY VAACRANVKS GAIMSALSDT EIQREIGISN ALHRLKLRLA IQEMVSLTSP
SAPPTSRTSS GNVWVTHEEM ETLETSTKTV SLALGLWPWT LAYGDMNHEW IGNEWLPSLG
LPQYRSYFME CLVDARMLDH LTKKDLRVHL KMVDSFHRTS LQYGIMCLKR LNYDRKELEK
RREESQHEIK DVLVWTNDQV VHWVQSIGLR DYAGNLHESG VHGALLALDE NFDHNTLALI
LQIPTQNTQA RQVMEREFNN LLALGTDRKL DDGDDKVFRR APSWRKRFRP REHHGGGGML
SASAETLPAG FRVSTLGSLQ PPPAPPKKIM PEGEPSQVRA PSWHPGAGPG GEGRGRGWCP
ALSGCRCTNA PRGACARTNP PLCVFSRGCR LLPAGTAGAQ RLETSTVRTY SC
//
