ID   A0A2K5P4J5_CERAT        Unreviewed;       520 AA.
AC   A0A2K5P4J5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Forkhead box N4 {ECO:0000313|Ensembl:ENSCATP00000044620.1};
GN   Name=FOXN4 {ECO:0000313|Ensembl:ENSCATP00000044620.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000044620.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000044620.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR   AlphaFoldDB; A0A2K5P4J5; -.
DR   STRING; 9531.ENSCATP00000044620; -.
DR   Ensembl; ENSCATT00000069062.1; ENSCATP00000044620.1; ENSCATG00000044785.1.
DR   GeneTree; ENSGT00940000158984; -.
DR   Proteomes; UP000233060; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000987; F:cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0035881; P:amacrine cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0010842; P:retina layer formation; IEA:Ensembl.
DR   GO; GO:0060579; P:ventral spinal cord interneuron fate commitment; IEA:Ensembl.
DR   CDD; cd20057; FH_FOXN4; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR049624; FOXN1_4.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46721:SF3; FORK-HEAD DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46721; FORKHEAD BOX PROTEIN N1; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          196..292
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        196..292
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          95..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          368..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          500..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..144
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        379..401
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  55670 MW;  7F2FEFCB72311B0D CRC64;
     MIESDISSIM SGIIRNSGQN HHPSPQEYRL LATTSDDDLP GDLQSLSWLT AVDVPRLQQM
     ASGRVDLGGP CVPHPHPGRL RDRCDIGKGV IPTTPSPLLH GPAGMAPGGM PGLGPITGHG
     DSMSQFPVGG QSSSGLQDPP HLYSPATQPQ FPLPPGAQQC PPVGLYGPPF GVRPPYPQPH
     MAVHSSQELH PKHYPKPIYS YSCLIAMALK NSKTGSLPVS EIYSFMKEHF PYFKTAPDGW
     KNSVRHNLSL NKCFEKVENK MSGSSRKGCL WALNLARIDK MEEEMHKWKR KDLAAIHRSM
     ANPEELDKLI SDRPESCRRP GKPGEPEAPV LTHATTVAVA HGCLAVSQLP PQPLMTLSLQ
     SVPLHHQVQP RAHLAPDSPA PAQTPPLHAL PDLSPSPLPH PAMGRAPVDF INISTDMNTE
     VDALDPSIMD FALQGNLWEE MKDEGFSLDT LGAFGDSPLG CDLGASGLTP ASGGSDQSFP
     DLQVTGLYTA YSTPDSVAAS GTSSSSQYLG AQGNKPIALL
//