ID A0A2K5P4U2_CERAT Unreviewed; 617 AA.
AC A0A2K5P4U2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Double-stranded RNA-binding protein Staufen homolog 2 {ECO:0000256|ARBA:ARBA00024122};
GN Name=STAU2 {ECO:0000313|Ensembl:ENSCATP00000044731.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000044731.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000044731.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5P4U2; -.
DR STRING; 9531.ENSCATP00000044731; -.
DR Ensembl; ENSCATT00000069173.1; ENSCATP00000044731.1; ENSCATG00000044825.1.
DR GeneTree; ENSGT00940000154977; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000044825; Expressed in frontal cortex and 12 other cell types or tissues.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003725; F:double-stranded RNA binding; IEA:Ensembl.
DR CDD; cd19882; DSRM_STAU2_rpt2; 1.
DR CDD; cd19884; DSRM_STAU2_rpt3; 1.
DR CDD; cd19886; DSRM_STAU2_rpt4; 1.
DR CDD; cd19888; DSRM_STAU2_rpt5; 1.
DR Gene3D; 3.30.160.20; -; 5.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR044464; STAU2_DSRM_2.
DR InterPro; IPR044473; STAU2_DSRM_3.
DR InterPro; IPR044474; STAU2_DSRM_4.
DR InterPro; IPR032478; Staufen_C.
DR PANTHER; PTHR46054:SF1; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2; 1.
DR PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR Pfam; PF00035; dsrm; 3.
DR Pfam; PF16482; Staufen_C; 1.
DR SMART; SM00358; DSRM; 3.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 4.
DR PROSITE; PS50137; DS_RBD; 3.
PE 4: Predicted;
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 104..190
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 216..283
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 316..384
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 587..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 67031 MW; 5BA0B015F8462CA9 CRC64;
MPGRRAEAGG GGGRGARGVE AGGGRAGSVL CTVCQCWSRL QSVPGKKMFS VQLSLGEQTW
ESEGSSIKKA QQAVANKALT ESTLPKPVQK PPKSNVNNNP GSITPTVELN GLAMKRGEPA
IYRPLDPKPF PNYRANYNFR GMYNQRYHCP VPKIFYVQLT VGNNEFFGEG KTRQAARHNA
AMKALQALQN EPIPERSPQN GESGKDMDDD KDANKSEISL VFEIALKRNM PVSFEVIKES
GPPHMKSFVT RVSVGEFSAE GEGNSKKLSK KRAATTVLQE LKKLPPLPVV EKPKLFFKKR
PKTIVKAGPE YGQGMNPISR LAQIQQAKKE KEPDYVLLSE RGMPRRREFV MQVKVGNEVA
TGTGPNKKIA KKNAAEAMLL QLGYKASTNL QDQLEKTGEN KGWSGPKPGF PEPTNNTPKG
ILHLSPDVYQ EMEASRHKVI SGTTLGYLSP KDMNQPSSSF FSISPTSNSS ATIARELLMN
GTSSTAEAIG LKGSSPTPPC SPVQPSKQLE YLARIQGFQV HYCDRQSGKE CVTCLTLAPV
QMTFHAIGSS IEASHDQAAL SALKQFSEQG LDPIDGAMNI EKGSLEKQAK HLREKADNNQ
APPGSIAQDC KKSNSAV
//
