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Database: UniProt
Entry: A0A2K5P802_CERAT
LinkDB: A0A2K5P802_CERAT
Original site: A0A2K5P802_CERAT 
ID   A0A2K5P802_CERAT        Unreviewed;       460 AA.
AC   A0A2K5P802;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   10-OCT-2018, entry version 5.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCATP00000045829};
GN   Name=TRPC4 {ECO:0000313|Ensembl:ENSCATP00000045829};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000045829, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000045829, ECO:0000313|Proteomes:UP000233060}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Liu Y., Hughes D.S., Murali S., Raveendran M., Korchina V., Wang M.,
RA   Jhangiani S., Bandaranaike D., Bellair M., Blankenburg K., Chao H.,
RA   Dahdouli M., Dinh H., Doddapaneni H., English A., Firestine M.,
RA   Gross S., Hernandez B., Javaid M., Jayaseelan J., Jones J., Joshi V.,
RA   Khan Z., Kovar C., Lee S., Newsham I., Nguyen L., Okwuonu G.,
RA   Ongeri F., Osuji N., Pu L.-L., Puazo M., Qu C., Quiroz J., Raj R.,
RA   Reid J.G., Santibanez J., Scheel M., Sexton D., Shah N., Skinner E.,
RA   Vee V., Wu Y., Han Y., Muzny D.M., Richards S., Worley K.C.,
RA   Rogers J., Gibbs R.A.;
RT   "Sooty reference genome and diversity panel.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCATP00000045829}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS01006510}.
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DR   Ensembl; ENSCATT00000070277; ENSCATP00000045829; ENSCATG00000045261.
DR   GeneTree; ENSGT00760000119180; -.
DR   Proteomes; UP000233060; Whole Genome Shotgun Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005460; TRPC4_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   PANTHER; PTHR10117:SF25; PTHR10117:SF25; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00933366}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000233060};
KW   Ion channel {ECO:0000256|SAAS:SAAS00790162};
KW   Ion transport {ECO:0000256|SAAS:SAAS00790154};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00788392}.
FT   TRANSMEM    331    350       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    362    384       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    396    416       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    436    457       Helical. {ECO:0000256|SAM:Phobius}.
FT   REPEAT      141    173       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   DOMAIN      141    173       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   COILED      227    254       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   460 AA;  53120 MW;  C4E1FE84D1A51235 CRC64;
     MAQFYYKRNV NAPYRDRIPL RIVRAESELS PSEKAYLNAV EKGDYASVKK SLEEAEIYFK
     ININCIDPLG RTALLIAIEN ENLELIELLL SFNVYVGDAL LHAIRKEVVG AVELLLNHKK
     PSGEKQVPPI LLDKQFSEFT PDITPIILAA HTNNYEIIKL LVQKGVSVPR PHEVRCNCVE
     CVSSSDVDSL RHSRSRLNIY KALASPSLIA LSSEDPFLTA FQLSWELQEL SKVENEFKSE
     YEELSRQCKQ FAKDLLDQTR SSRELEIILN YRDDNSLIEE QSGNDLARLK LAIKYRQKEF
     VAQPNCQQLL ASRWYDEFPG WRRRHWAVKM VTCFIIGLLF PVFSVCYLIA PKSPLGLFIR
     KPFIKFICHT ASYLTFLFLL LLASQHIDRS DLNRQGPPPT IVEWMILPWV LGFIWGEIKQ
     MWDGGLQDYI HDWWNLMDFV MNSLYLATIS LKIVAFVKVI
//
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