ID A0A2K5TJ25_MACFA Unreviewed; 640 AA.
AC A0A2K5TJ25;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=EF-hand domain containing 1 {ECO:0000313|Ensembl:ENSMFAP00000000032.1};
GN Name=EFHC1 {ECO:0000313|Ensembl:ENSMFAP00000000032.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000000032.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000000032.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000000032.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
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DR RefSeq; XP_005552808.1; XM_005552751.2.
DR AlphaFoldDB; A0A2K5TJ25; -.
DR Ensembl; ENSMFAT00000028197.2; ENSMFAP00000000032.1; ENSMFAG00000036082.2.
DR GeneID; 101926112; -.
DR KEGG; mcf:101926112; -.
DR CTD; 114327; -.
DR VEuPathDB; HostDB:ENSMFAG00000036082; -.
DR GeneTree; ENSGT00530000063528; -.
DR OMA; RYSARMD; -.
DR OrthoDB; 160134at2759; -.
DR Proteomes; UP000233100; Chromosome 4.
DR Bgee; ENSMFAG00000036082; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0005930; C:axoneme; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 2.30.29.170; -; 3.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF9; EF-HAND DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS51336; DM10; 3.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 93..198
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 239..359
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 416..520
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 574..609
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 640 AA; 73911 MW; D8F5CC1D6ACD3EE4 CRC64;
MVSNPVHGLP FLPGTSFKDS TKTAFHRSQT LGYRNGYAIV RRPTVGIGGD RLQFNQLSQA
ELDELASKAP VLTYGQPKQA PPADFIPAHV AFDKKVLKFD AYFQEDVPMS TEEQYRIRQV
NIYYYLEDDS MSVIEPVVEN SGIPQGKLIK RQRLAKNDRG DHYHWKDLNR GINITIYGKT
FRVVDCDQFT QVFLESQGIE LNPPEKMALD PYTELRKQPL RKYVTPSDFD QLKQFLTFDK
QVLRFYAIWD DTDSMYGECR TYIIHYYLMD DTVEIREVHE RNDGRDPFPL LMNRQRMPKV
LVENAKNFPQ CVLEISDQEV LEWYTAKDFI VGKSLTVLGR TFFIYDCDPF TRRYYKEKFG
ITDLPRIDVN KQEPPPVKQE LPPYNGFGLV EDSAQNCFAL IPKAPKKDVI KMLVNDNKVL
RYLAALESPI PEDKDRRFVF SYFLATDMIS IFEPPVRNSG IIGGKYLGRT KVVKPYSTVD
NPIYYGPSDF FIGAVIEVFG HRFIILDTDE YVLKYMESNA AQYSPEALAS VQKHVRKLEA
PASESESKQT EKDPGVQELE ALIDTIQKQL KDHSCKDDIR EAFQIYDKEA SGYVDRDMFF
KICESLNVPV DDSLVKELIR MCSHGEGKIN YYNFVRAFSN
//
