ID   A0A2K5TJK6_MACFA        Unreviewed;       796 AA.
AC   A0A2K5TJK6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=SH3 domain containing 21 {ECO:0000313|Ensembl:ENSMFAP00000000191.2};
GN   Name=SH3D21 {ECO:0000313|Ensembl:ENSMFAP00000000191.2};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000000191.2, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000000191.2, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000000191.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5TJK6; -.
DR   Ensembl; ENSMFAT00000028357.2; ENSMFAP00000000191.2; ENSMFAG00000036528.2.
DR   VEuPathDB; HostDB:ENSMFAG00000036528; -.
DR   GeneTree; ENSGT00940000160627; -.
DR   Proteomes; UP000233100; Chromosome 1.
DR   Bgee; ENSMFAG00000036528; Expressed in adult mammalian kidney and 6 other cell types or tissues.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   CDD; cd11874; SH3_CD2AP-like_2; 1.
DR   CDD; cd12142; SH3_D21-like; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR035468; SH3D21_SH3.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR14167:SF28; SH3 DOMAIN-CONTAINING 21; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   Pfam; PF14604; SH3_9; 2.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 3.
DR   SUPFAM; SSF50044; SH3-domain; 3.
DR   PROSITE; PS50002; SH3; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          1..58
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          83..142
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          181..242
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          142..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          248..660
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          776..796
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        283..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..343
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..510
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        589..620
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   796 AA;  87470 MW;  12B09023603D7FDC CRC64;
     MEVLVLAGYR AQKEDELSLA PGDVVRQVRW VPARGWLRGE LGGRYGLFPE RLVQEIPETL
     RGSREAQRPR CARRRGHPAK YPGPQRWCKV NFNYSPEQAD ELKLQAGEIV EMIKEIEDGW
     WLGKKNGQLG AFPSNFVELL DSGPPSFGNP DMPSVSPGPQ RPPKLSSLAY DSPPDYLQTV
     SHPEAYRVLF DYQPEAPDEL TLRRGDVVKV LSKTTEDKGW WEGECQGRRG VFPDNFVLPP
     PPIKKLVPRK VVSRQSAPIK EPKKLMPKTS LPTVKKLATA ATGPSKAKTS RTPSRDSQKL
     TSRDSGPNGG FQSGGSCPPG RKRSKTQTPQ QRSVSSQEEE HSSPAKAPSV KRTPMLDKTT
     TPERPPAPEN APGSKKIPVP DKVPSPEKTL TLGDKASIPG NSTSGKIPAP DIVPTPERMV
     TPEDKASIPE NSIPEEALTV DKPSTPERLF SVEEASGPEV PPMDKVPDPK MAPLGDEAPT
     REKVLTPELS EEEVSTRDDT QFHHFSSEEA LQKVKSFVAK EAPSSQEKAH TPEAPPLQPP
     SSERCLGEMK CPLVRGDSSP HQAELKSGPA SRPALEKPHP QAEATTLLEE APSKEERTPE
     EEASPNEERP LREEVLPKEG VASKGEVLPK EGVASKGEVL PKEGVASKEV LPKGGVASKE
     EVLPKEGVAS KEEVTLKEEV APKEEVPPID TAFAQKTHPI KPSPDSQETL TLPSLLPQNY
     TENKNEGVDV TSLRGEVESL RRALELMGVQ LERKLTDIWE ELKSEKEQRQ RLEVQVMQGT
     QKSQTPRIIH AQTQTY
//