ID A0A2K5TN99_MACFA Unreviewed; 1358 AA.
AC A0A2K5TN99;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Ubiquitin specific peptidase 31 {ECO:0000313|Ensembl:ENSMFAP00000001521.2};
GN Name=USP31 {ECO:0000313|Ensembl:ENSMFAP00000001521.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000001521.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000001521.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000001521.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 9541.ENSMFAP00000001521; -.
DR Ensembl; ENSMFAT00000000048.2; ENSMFAP00000001521.2; ENSMFAG00000036053.2.
DR VEuPathDB; HostDB:ENSMFAG00000036053; -.
DR GeneTree; ENSGT00940000156355; -.
DR Proteomes; UP000233100; Chromosome 20.
DR Bgee; ENSMFAG00000036053; Expressed in temporal lobe and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:Ensembl.
DR CDD; cd02674; Peptidase_C19R; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR21646:SF44; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 31; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 128..769
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 816..839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..1358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..118
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1005
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1019..1033
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1070
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1103..1141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1162..1187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1205..1220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1221..1249
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1283..1299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1312..1358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1358 AA; 147813 MW; FDC2411803B0376E CRC64;
MSVCGRRHVQ GNGAWSGPPA AGGKEKRSFS KRLFRSGRAG GGAGAPRASG PAAPSSPSSP
SSARSVGSFM SRVLKTLSTL SHLSSEGAAP DRGGLRSCFP PGPAAAPTPP PCPPPPALSR
AAGLRRRASA RRGGTPQPWQ HVLHERHAAV PQQHRALRRV PGAGPVPGGR PEPSPDPEQP
AGRGAQGQGE VTEQLAHLVR ALWTLEYTPQ HSRDFKTIVS KNALQYRGNS QHDAQEFLLW
LLDRVHEDLN HSVKQSGQPP LKPPSETDMM PEGPFPVCST FVQELFQAQY RSSLTCPHCQ
KQSNTFDPFL CISLPIPLPH TRPLYVTVVY QGKCSHCMRI GVAVPLSGTV ARLREAVSME
TKIPTDQIVL TEMYYDGFHR SFCDTDDLET VHESDCIFAF ETPEIFRPEG ILSQRGIHLN
NNLNHLKFGL DYHRLSSPTQ TAAKQGKMDS STSRAGSDKI VLLVCNRACT GQQGKRFGLP
FVLHLEKTIA WDLLQKEILE KMKYFLRPTA CIQVCPFSLR VVSVVGITYL LPQEEQPLCH
PTVERALKSC GPGGTAHVKL VVEWDKETRD FLFANTEDEY IPDAESVRLQ RERHHQPQTC
TLSQCFQLYT KEERLAPDDA WRCPHCKQLQ QGSITLSLWT LPDVLIIHLK RFRQEGDRRM
KLQNMVKFPL TGLDMTPHVV KRSQSSWSLP SHWSPWRRPY GLGRDPEDYI YDLYAVCNHH
GTMQGGHYTA YCKNSVDGLW YCFDDSDVQQ LSEDEVCTQT AYILFYQRRT AIPSWSANSS
VAGSTSSSLC EHWVSRLPGS KPASVTSAAS SRRTSLASLS ESVEMTGERS EDDGGFSTRP
FVRSVQRQSL SSRSSVTSPL AVNENCMRPS WSLSAKLQMR SNSPSRFSGD SPIHSSASTL
EKIGEAADDK VSISCFGSLR NLSNSYQEPS DSHSRREHKA VGRAPLAVME GVFKDESDTR
RLNSSVIDTQ SKHSAQGDRL PPVSDPFDNN NQIAYVDQSD SVDNSPVKEV KPPSHPGSLT
KKPESTTKKS PSSKGTSEPE KSLRKGRPAL ASQESSLSST SPSSPLPVKV SLKPSRSRSK
ADSSSRGSGR HSSPAPAPAQ PRKESSPKSQ DSVSSPSPQK QKSASALTYT ASSTSAKKAS
GPATRSPFPP GKSRTSDRSL SREGSRQSLG SDRASATSAS KPNSPRVSQA RAGEGRGAGR
HVRSSSMASL RSPSASIKSG LKRDSKSEDK GLSFFKSALR QKETRRSTDL GKTALLSKKA
GGSSVKSVCK NTGDDKGEKG HQPPASQQPN ANATGKEQLV SKDPASAKHS LLSARKSKSS
QLDSGVPSSP GSRQSAEKSS KKLSSSMQTS ARPSQKPQ
//
