ID A0A2K5TRM4_MACFA Unreviewed; 821 AA.
AC A0A2K5TRM4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Semaphorin 4B {ECO:0000313|Ensembl:ENSMFAP00000002693.2};
GN Name=SEMA4B {ECO:0000313|Ensembl:ENSMFAP00000002693.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000002693.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000002693.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000002693.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A2K5TRM4; -.
DR STRING; 9541.ENSMFAP00000002693; -.
DR Ensembl; ENSMFAT00000027841.2; ENSMFAP00000002693.2; ENSMFAG00000034089.2.
DR VEuPathDB; HostDB:ENSMFAG00000034089; -.
DR GeneTree; ENSGT00940000154870; -.
DR Proteomes; UP000233100; Chromosome 7.
DR Bgee; ENSMFAG00000034089; Expressed in lymph node and 12 other cell types or tissues.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0098839; C:postsynaptic density membrane; IEA:Ensembl.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd05872; Ig_Sema4B_like; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF14; SEMAPHORIN-4B; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 702..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..507
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 821 AA; 90410 MW; CF69EFE92EB9B608 CRC64;
MGRAAASATA AAPAAAASAA AATSDLGAQP RISLPLGSEE RPFLRFEAEN ISNYTALLLS
RDGRTLYVGA REALFALNSN LSFLPGGEYQ ELLWSADAEK KQQCSFKGKD PQRDCQNYIK
ILLPLSSSHL FTCGTAAFSP MCTYINVENF TLARDEKGNV LLEDGKGRCP FDPNFKSTAL
VVDGELYTGT VSSFQGNDPA ISRSQSLRPT KTESSLNWLQ DPAFVASAYI PESLGSLQGD
DDKIYFFFSE TGQEFEFFEN TIVSRIARIC KGDEGGERVL QQRWTSFLKA QLLCSRPDDG
FPFNVLQDVF TLSPSPQDWR DTLFYGVFTS QWHRGTTEGS AICVFTMKDV QRVFSGLYKE
VNRETQQWYT VTHPVPTPRP GACITNSARE RKINSSLQLP DRVLNFLKDH FLMDGQVRSR
MLLLQPQARY QRVAVHRVPG LHHAYDVLFL GTGDGRLHKA VSVGPRVHII EELQIFSSGQ
PVQNLLLDTH RGLLYAASHS GVVQVPVANC SLYRSCGDCL LARDPYCAWS GSSCKHVSLY
QPELATRPWI QDIEGANAKD LCSISSVVSL SFVPTGEKPC KQVQFQPNTV NTLACPLLSN
LATRLWLHNG APINASASCH VLPTGDLLLV GTQQLGEFQC WSLEEGFQQL VASYCPEVVE
DGVADQTDQR GSVPVIISTS RVSAPAGGQA SWGADKSYWK EFLVMCTLFV LAVLFPVLFL
LYRHRNSMKV FLKQGECASV HPKTCPVVLP PETRPLNGLG PPSTPLDHRG YQALSDSPPG
ARVFTESEKR PLSIQDSFVE VSPVCPRPRV RLGSEIRDSV V
//
