ID A0A2K5U061_MACFA Unreviewed; 667 AA.
AC A0A2K5U061;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Zinc finger protein 133 {ECO:0000313|Ensembl:ENSMFAP00000005724.2};
GN Name=ZNF133 {ECO:0000313|Ensembl:ENSMFAP00000005724.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000005724.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000005724.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000005724.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K5U061; -.
DR Ensembl; ENSMFAT00000024404.2; ENSMFAP00000005724.2; ENSMFAG00000002522.2.
DR VEuPathDB; HostDB:ENSMFAG00000002522; -.
DR GeneTree; ENSGT00940000162260; -.
DR Proteomes; UP000233100; Chromosome 10.
DR Bgee; ENSMFAG00000002522; Expressed in skeletal muscle tissue and 13 other cell types or tissues.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 15.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24394:SF45; ZINC FINGER PROTEIN 771; 1.
DR Pfam; PF00096; zf-C2H2; 14.
DR SMART; SM00355; ZnF_C2H2; 15.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 227..254
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 255..282
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 283..310
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 311..338
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 339..366
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 367..394
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 395..422
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 423..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 451..478
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 479..506
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 507..534
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 535..562
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 563..590
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 591..618
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 619..649
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 73824 MW; 100B905F806189E2 CRC64;
MGAAGRQGAP GGAEHPGRCG PGAVPRIRGS VVLAPRWRSS PAGGWSDPLF FGGAGISFSK
PELITQLEQG KETWREEKNC SPATCPDPEP ELYLDPFCPP GFSSQKFPMQ HVLCNHPPWI
FTCLCTEGDV QPGDPGPGDE QKQPQASEGR PWSDEAEGPG GEGARPLFGR TKKRTLGAFS
RPPQRQPVTS RNSLRGVELE ASPAPTGNPE ETDKLLKRIE VLGFGTVNCG ECGLSFSKMT
NLLSHQRIHS GEKPYVCGVC EKGFSLKKSL ARHQKAHSGE KQIVCSECGR GFNRKSTLII
HERTHSGEKP YMCSECGRGF SQKSNLIIHQ RTHSGEKPYV CRECGKGFSQ KSAVVRHQRT
HLEEKTIVCS DCGLGFSDRS NLISHQRTHS GEKPYACKEC GRCFRQRTTL VNHQRTHSKE
KPYVCGVCGH SFSQNSTLIS HRRTHTGEKP YVCGVCGRGF SLKSHLNRHQ NIHSGEKPIV
CKDCGRGFSQ QSNLIRHQRT HSGEKPMVCG ECGRGFSQKS NLVAHQRTHS GERPYVCREC
GRGFSHQAGL IRHKRKHSRE KPYMCRQCGL GFGNKSALIT HKRAHLEEKP CVCRECGQGF
LQKSHLTLHQ MAHKGEKPYV CKTCGQGFSL KSHLSRHRKT KSVHHRLPPH PDPEPCAGQP
SDSLYSL
//
