ID A0A2K5U125_MACFA Unreviewed; 852 AA.
AC A0A2K5U125;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=PHD finger protein 14 {ECO:0000313|Ensembl:ENSMFAP00000006061.2};
GN Name=PHF14 {ECO:0000313|Ensembl:ENSMFAP00000006061.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000006061.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000006061.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000006061.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5U125; -.
DR Ensembl; ENSMFAT00000024741.2; ENSMFAP00000006061.2; ENSMFAG00000002668.2.
DR VEuPathDB; HostDB:ENSMFAG00000002668; -.
DR GeneTree; ENSGT00940000156923; -.
DR Proteomes; UP000233100; Chromosome 3.
DR Bgee; ENSMFAG00000002668; Expressed in thymus and 13 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15674; ePHD_PHF14; 1.
DR CDD; cd15561; PHD1_PHF14; 1.
DR CDD; cd15562; PHD2_PHF14; 1.
DR Gene3D; 2.30.30.1150; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF150; PHD FINGER PROTEIN 14; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..852
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030050685"
FT DOMAIN 296..357
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 359..476
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 702..756
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 17..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 607..655
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 48..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..233
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 96077 MW; 8C842A62F9A0E7F3 CRC64;
MYIHMCGFFF LIFSTDSEGS GNGSEDASKD SGEGSCSDSE ENILEEELNE DIKVKEEQLK
NSAEEVLSAE KQLIKMEKKE EEENGERPRK KKEKEKEKEK EKEKEKEREK EKEKATVSEN
VAPSAAATTP ATSPPAVNTS PSVPTVTTAA EEQVSEPKKW NLRRNRPLLD FVSMEELNDM
DDYDSEDDND WRPTVVKRKG RSASQKEGSD GDNEDDEDEG SGSDEDENDE GNDEDHSSPA
SEGGCKKKKS KVLSRNSADD EELTNDSLTL SQSKSNEDSL ILEKSQNWSS QKMDHILICC
VCLGDNSEDA DEIIQCDNCG ITVHEGCYGV DGESDSIMSS ASENSTEPWF CDACKCGVSP
SCELCPNQDG IFKETDAGRW VHIVCALYVP GVAFGDIDKL RPVTLTEMNY SKYGAKECSF
CEDPRFARTG VCISCDAGMC RAYFHVTCAQ KEGLLSEAAA EEDIADPFFA YCKQHADRLD
RKWKRKNYLA LQSYCKMSLQ EREKQLSPEA QARINARLQQ YRAKAELARS TRPQAWVPRE
KLPRPLTSSA SAIRKLMRKA ELMGISTDIF PVDNSDTSSS VDGRRKHKQP ALTADFVNYY
FERNMRMIQI QENMAEQKNI KDKLENEQEK LHVEYNKLCE SLEELQNLNG KLRSEGQGIW
ALLGRITGQK LNIPAILRAP KERKPSKKEG GTQKTSTLPA VLYSCGICKK NHDQHLLLLC
DTCKLHYHLG CLDPPLTRMP RKTKNSYWQC SECDQAGSSD MEADMAMETL PDGTKRSRRQ
IKEPVKFVPQ DVPPEPKKIP IRNTERVPRE RRQRQSVLQK KPKAEDLRTE CATCKGTGDN
ENLVRVLFLI IY
//
