ID A0A2K5U6V6_MACFA Unreviewed; 603 AA.
AC A0A2K5U6V6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=HAUS augmin like complex subunit 3 {ECO:0000313|Ensembl:ENSMFAP00000008092.1};
GN Name=HAUS3 {ECO:0000313|Ensembl:ENSMFAP00000008092.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000008092.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000008092.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000008092.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the HAUS3 family.
CC {ECO:0000256|ARBA:ARBA00009645}.
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DR RefSeq; XP_005554361.1; XM_005554304.2.
DR RefSeq; XP_015305520.1; XM_015450034.1.
DR AlphaFoldDB; A0A2K5U6V6; -.
DR STRING; 9541.ENSMFAP00000008092; -.
DR Ensembl; ENSMFAT00000026788.2; ENSMFAP00000008092.1; ENSMFAG00000034116.2.
DR GeneID; 102134939; -.
DR KEGG; mcf:102134939; -.
DR CTD; 79441; -.
DR VEuPathDB; HostDB:ENSMFAG00000034116; -.
DR GeneTree; ENSGT00390000011904; -.
DR OMA; LEWFCGN; -.
DR OrthoDB; 1110803at2759; -.
DR Proteomes; UP000233100; Chromosome 5.
DR Bgee; ENSMFAG00000034116; Expressed in temporal lobe and 13 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0070652; C:HAUS complex; IEA:Ensembl.
DR GO; GO:1990498; C:mitotic spindle microtubule; IEA:Ensembl.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007098; P:centrosome cycle; IEA:Ensembl.
DR GO; GO:0051225; P:spindle assembly; IEA:Ensembl.
DR InterPro; IPR026206; HAUS3.
DR InterPro; IPR032733; HAUS3_N.
DR PANTHER; PTHR19378; GOLGIN- RELATED; 1.
DR PANTHER; PTHR19378:SF0; HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3; 1.
DR Pfam; PF14932; HAUS-augmin3; 1.
DR PRINTS; PR02089; HAUSAUGMINL3.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 29..281
FT /note="HAUS augmin-like complex subunit 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14932"
FT COILED 307..334
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 603 AA; 69538 MW; 30C96BBB15783F0C CRC64;
MSCGNEFVET LKKIGFPKAD NLNGEDFDWL FEGIEDESFL KWFCGNVNEQ NVLSERELEA
FSVLQKSGKP ILEGAALDEA LKTCKTSDLK TPRLDDKELE KLEDEVQTLL KLKNLKIQRR
NKCQLMASVT SHKSLRLNAK EESATKKLKQ SQGILNAVNT KISNELQALT DEVTQLMMFF
RHSNLGQGTN PLVFLSQFSL EKYLSQEEQS TAALTLYTKK QFFQGIHEVV ESSNEDNFQL
LDIQTPSICD NQEILEERRL EMARLQLAYI CAQHQLIHLK ASNSSMKSSI KWAEETLHSL
TSKAVDKENL DAKISSLTSE IMKLEEQITQ IKDRSLPAVV RENAQLLNMP VVKGDFDLQI
AKQDYYTARQ ELVLNQLIKQ KASFELLQLS YEIELRKHWD IYRELENLVQ ELSQSNMMLY
KQLEILTDPS VSQQINPRNT IDTKDYSTHR LYQLLEGENK KKELFLTHGN LEEVAEKLKQ
NVSLVQDQLA VSAQEHSFFL SKRNKDVDML CDALYQGGNQ LLLSDQELTE QFHQVESQLN
KLNHLLTDIL ADVKTKRKTL ANNKLHQMER ELYVYFLKDE DYLKDIVENL ETQSKIKAVS
LED
//
