ID A0A2K5U7R8_MACFA Unreviewed; 369 AA.
AC A0A2K5U7R8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Cytohesin 4 {ECO:0000313|Ensembl:ENSMFAP00000008395.2};
GN Name=CYTH4 {ECO:0000313|Ensembl:ENSMFAP00000008395.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000008395.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000008395.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000008395.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5U7R8; -.
DR Ensembl; ENSMFAT00000021660.2; ENSMFAP00000008395.2; ENSMFAG00000001277.2.
DR VEuPathDB; HostDB:ENSMFAG00000001277; -.
DR GeneTree; ENSGT00940000160865; -.
DR Proteomes; UP000233100; Chromosome 10.
DR Bgee; ENSMFAG00000001277; Expressed in spleen and 11 other cell types or tissues.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF323; CYTOHESIN-4; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 54..241
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT COILED 19..53
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 369 AA; 42282 MW; E5C35415F08C7EC4 CRC64;
MDLCHPEPAE LSSGETEELQ RIKWHRKQLL EDIQKLKDEI ADVFAQIDCF ESAEESRMAQ
KEKELCTGRK KFNMDPAKGI QYFIEHKLLT PDIQDIARFL YKGEGLNKTA IGTYLGERDP
VNLQVLQAFV DCHEFANLNL VQALRQFLWS FRLPGEAQKI DRMMEAFATR YCLCNPGVFQ
STDTCYVLSF SIIMLNTSLH NPNVRDRPPF ERFVSMNRGI NNGSDLPEDQ LRNLFDSIKS
EPFSIPEDDG NDLTHTFFNP DREGWLLKLG ERPTDTRRRM HIHAHAGTHC HTHTHARVGT
HRHTHTDTRV STRRCMHTYA RTDTRLTRGS HASWGMELDS LQVSWPPVQP SACPIHPSVL
RMKGASGGG
//
