ID A0A2K5UIJ5_MACFA Unreviewed; 202 AA.
AC A0A2K5UIJ5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Calpain 3 {ECO:0000313|Ensembl:ENSMFAP00000012219.2};
GN Name=CAPN3 {ECO:0000313|Ensembl:ENSMFAP00000012219.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000012219.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000012219.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000012219.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A2K5UIJ5; -.
DR Ensembl; ENSMFAT00000056411.2; ENSMFAP00000012219.2; ENSMFAG00000008163.2.
DR VEuPathDB; HostDB:ENSMFAG00000008163; -.
DR GeneTree; ENSGT00940000156092; -.
DR Proteomes; UP000233100; Chromosome 7.
DR Bgee; ENSMFAG00000008163; Expressed in skeletal muscle tissue and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd16190; EFh_PEF_CAPN3; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR029531; CAPN3_PEF.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR46735; CALPAIN, SMALL SUBUNIT 1 A-RELATED; 1.
DR PANTHER; PTHR46735:SF3; CALPAIN, SMALL SUBUNIT 1 A-RELATED; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 103..138
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 168..202
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 202 AA; 23402 MW; 7388C0AD675BB551 CRC64;
MGSSRAHRRV LDWSGGLVEP QPGSSDQESE EQQQFRNIFK QIAGDDMEIC ADELKKVLNT
VVNKHKDLKT HGFTLESCRS MIALMDTDGS GKLNLQEFHH LWNKIKAWQK IFKHYDTDQS
GTINSYEMRN AVNDAGFHLN NQLYDIITMR YADKHMNIDF DSFICCFVRL EGMFRAFHAF
DKDGDGIIKL NVLEWLQLTM YA
//
