ID A0A2K5UQA7_MACFA Unreviewed; 838 AA.
AC A0A2K5UQA7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=G protein-coupled receptor associated sorting protein 2 {ECO:0000313|Ensembl:ENSMFAP00000014564.1};
GN Name=GPRASP2 {ECO:0000313|Ensembl:ENSMFAP00000014564.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000014564.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000014564.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000014564.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPRASP family.
CC {ECO:0000256|ARBA:ARBA00011013}.
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DR RefSeq; XP_005594239.1; XM_005594182.2.
DR RefSeq; XP_005594240.1; XM_005594183.2.
DR RefSeq; XP_005594241.1; XM_005594184.2.
DR RefSeq; XP_005594242.1; XM_005594185.2.
DR RefSeq; XP_015299281.1; XM_015443795.1.
DR RefSeq; XP_015299282.1; XM_015443796.1.
DR RefSeq; XP_015299283.1; XM_015443797.1.
DR RefSeq; XP_015299284.1; XM_015443798.1.
DR RefSeq; XP_015299285.1; XM_015443799.1.
DR STRING; 9541.ENSMFAP00000014564; -.
DR Ensembl; ENSMFAT00000065060.2; ENSMFAP00000014564.1; ENSMFAG00000030449.2.
DR Ensembl; ENSMFAT00000079826.1; ENSMFAP00000063727.1; ENSMFAG00000030449.2.
DR Ensembl; ENSMFAT00000101996.1; ENSMFAP00000052045.1; ENSMFAG00000030449.2.
DR GeneID; 102138501; -.
DR KEGG; mcf:102138501; -.
DR VEuPathDB; HostDB:ENSMFAG00000030449; -.
DR GeneTree; ENSGT00940000162726; -.
DR OMA; WPREEAN; -.
DR Proteomes; UP000233100; Chromosome X.
DR Bgee; ENSMFAG00000030449; Expressed in pituitary gland and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0001540; F:amyloid-beta binding; IEA:Ensembl.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:Ensembl.
DR GO; GO:0061484; P:hematopoietic stem cell homeostasis; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR006911; ARM-rpt_dom.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR043374; GASP1-3.
DR PANTHER; PTHR46414:SF1; G-PROTEIN COUPLED RECEPTOR-ASSOCIATED SORTING PROTEIN 2; 1.
DR PANTHER; PTHR46414; PROTEIN BHLHB9-RELATED; 1.
DR Pfam; PF04826; Arm_2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 595..812
FT /note="Armadillo repeat-containing"
FT /evidence="ECO:0000259|Pfam:PF04826"
FT REGION 1..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 93642 MW; C31FC11EAE696C58 CRC64;
MTGAEIEPSA QAKPEKKAGE EVIAGAEREN DVPLVVRPKV RTQATTGARP KTETKSVPGA
RPKTDAQAMS GARPKTEAQV MGGARPKTEA QGMAGARPKT DARAVGGARP KTDAKAIPGT
RPKDEAQAWA QSEFGTEAVS QAEGVSQTNA VAWPLATAES GSVNKSKGLS MDRELVDVDA
ETFPGTQGQK GIQPWFGPGE ETNMGSWCYS RPRAREEASN ESGFWSADET STVSSFWAGE
ETSIRSWPRE DSNTRSRHRA KHQTNPRSRP RSKQEAYVDS WSGSEDEAGN LFAFWAGENT
SNLFRPRVRE EANIRSKLRT NREDCFESES EDEFYKQSWV LPGEEANGRF RCRDKEDPNT
ALKPRAQKDV DGDRVKQEPR FEEEVIIGSW FWAEKEASLE GGASAICESE PGTEEGAIGG
STYWAEEKSS LGAVAREEAK PESEEEAIFG SWFWDRDEAC FDLNPCPVYK VSDRFRDAAE
ELNASSRPQT WEEVTVEFKP GLFHGVGFRS TSPFRIPEEA SEILEAKPKN MELSPEGEEQ
ESLLQPNQPD PEFTFQYDPS YRSVREIREH LRARESAESE GWSCSCIQCE LKIGSEEFEE
LLLLMDKIRD PFIHEISKIA MGMRSASQFT RDFIRDSGVV SLIETLLNYP SSRVRTSFLE
NMIHMAPPYP NLNMIETFIC QVCEETLAHS VDSLEQLTGI RMLRHLTMTI DYHTLIANYM
SGFLSLLTTA NARTKFHVLK MLLNLSENPA VAKKLFSAKA LSIFVGLFNI EETNDNIQIV
IKMFQNISNI IKSGKMSLID DDFSLEPLIS AFREFEELAK QLQAQIDNQN DPEVGQQS
//
