ID   A0A2K5UR81_MACFA        Unreviewed;       250 AA.
AC   A0A2K5UR81;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=IZUMO1 receptor, JUNO {ECO:0000313|Ensembl:ENSMFAP00000014946.2};
GN   Name=IZUMO1R {ECO:0000313|Ensembl:ENSMFAP00000014946.2};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000014946.2, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000014946.2, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000014946.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the folate receptor family.
CC       {ECO:0000256|ARBA:ARBA00007932}.
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DR   AlphaFoldDB; A0A2K5UR81; -.
DR   STRING; 9541.ENSMFAP00000014946; -.
DR   Ensembl; ENSMFAT00000065460.2; ENSMFAP00000014946.2; ENSMFAG00000030684.2.
DR   VEuPathDB; HostDB:ENSMFAG00000030684; -.
DR   GeneTree; ENSGT00950000183144; -.
DR   Proteomes; UP000233100; Chromosome 14.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:Ensembl.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane involved in single fertilization; IEA:Ensembl.
DR   GO; GO:0035036; P:sperm-egg recognition; IEA:Ensembl.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   PANTHER; PTHR10517; FOLATE RECEPTOR; 1.
DR   PANTHER; PTHR10517:SF10; SPERM-EGG FUSION PROTEIN JUNO; 1.
DR   Pfam; PF03024; Folate_rec; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..250
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030051078"
FT   DOMAIN          26..208
FT                   /note="Folate receptor-like"
FT                   /evidence="ECO:0000259|Pfam:PF03024"
SQ   SEQUENCE   250 AA;  28721 MW;  29324312194A9C11 CRC64;
     MAWWWPLLLE LLTVMPTWAG DELLNICMNA KHHKRVPGPE DKLYEECIPW KDNACCTLTT
     SWEAHLDVSP LYNFSLFHCG LLMPGCRKHF IQAICFYECS PNLGPWIRPV GSLGWEEAPS
     RQGERVVNAP LCQEDCEEWW EDCRLSYTCK SNWRGGWDWS QGKNRCPKGA QCLPFSHYFP
     TPADLCEKTW SNSFKASPER RNSGQCLQKW FEPAQGNPNV AVARLFASSA PSWELSYTLM
     VCSVFLPFLS
//