ID A0A2K5UZX8_MACFA Unreviewed; 1051 AA.
AC A0A2K5UZX8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=BUB1 mitotic checkpoint serine/threonine kinase B {ECO:0000313|Ensembl:ENSMFAP00000017978.2};
GN Name=BUB1B {ECO:0000313|Ensembl:ENSMFAP00000017978.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000017978.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000017978.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000017978.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_015308127.1; XM_015452641.1.
DR AlphaFoldDB; A0A2K5UZX8; -.
DR STRING; 9541.ENSMFAP00000017978; -.
DR Ensembl; ENSMFAT00000068521.2; ENSMFAP00000017978.2; ENSMFAG00000032047.2.
DR GeneID; 102133579; -.
DR CTD; 701; -.
DR VEuPathDB; HostDB:ENSMFAG00000032047; -.
DR GeneTree; ENSGT00940000158912; -.
DR OrthoDB; 5479089at2759; -.
DR Proteomes; UP000233100; Chromosome 7.
DR Bgee; ENSMFAG00000032047; Expressed in thymus and 4 other cell types or tissues.
DR GO; GO:0000776; C:kinetochore; IEA:UniProt.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR PANTHER; PTHR14030:SF25; MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 62..226
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT REGION 369..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 119610 MW; 2056C9E419F526C0 CRC64;
MAAVKKEGGA LSEAMSLEGD EWELSKENVQ PLRQGRIMST LQGALAQESA CNNTLQQQKR
AFESEIRFYT GHDPLDVWDR YISWTEQNYP QGGKESNMST LLERAVEALQ GEKRYYSDPR
FLNLWLKLGR LCNEPLDMYS YLHNQGIGVS LAQFYISWAE EYEARENFRK ADAIFQEGIQ
QKAEPLERLQ SQHRQFQARV SRQTLLALEK EEEEEVFESS VPQRSTLAEL KSKGKKTARA
PIIRVGGALK APSQNRGLQN PFPQQMQSNS RITVFDENAD EASIAELSKP TVQPWIAPPV
PRAKENELQA GPWNTGRSLE YRPRGNTASL MAVPAVLPSF TPYVEETAQQ PVMTPCKIEP
SINHILSTRK PGKEEGDPLQ RVQSHQQASE EKKEKMMYCK EKIYAGVGEF SFEEIRAEVF
RKKLKEQREA ELLTSAEKRA EMQKQIEEME KKLKEIQTTQ QERTGDQQEE TMPTKETTKL
RIASESQEMP GMTLSSSACQ VNSCAKETSL AENIWQEQPH SKGPSIPFSI FDEFLLSEKK
NKSPPADPPR VLTQRRPLAV LKTSESITSN EDVSPDVCDE FTEIEPLSED AIITGFRNVT
ICPNPEDTCD FARAARFVST PFHEIMSLKN LPSDPERLLQ EEDLDVKTSE DQQAACGTIY
SQTLSIKKLS PIIEDSREAT HSSGFSGSSA SVASTSSIKC LQIPEKLELT NETSAENPTQ
SPWCSQYRRQ LLKSLPELSA SAELCIEDRP MPKLEIEKEI ELGNEDYCIK REYLICEDYK
LFWVAPRNSA ELTIIKVSSQ PVPWDFYINL KLKERLNEAF DHLCSCYQYQ DGCIVWHQYI
NCFTLQDLLQ HSEYITHEIA VLIIYNLLTI VEKLHKAEIV HGDLSPRSLI LRNRIHDPYD
CNENNQALKI VDFSYSVDLR VQLDVFTLSG FRTVQILEGQ KILANCSSPY QVDLFGIADL
AHLLLFKEHL QVFWDGSFWK LSQNISELKD GELWNKFFVR ILNANDEATV SVLRELAAEM
NGVFDTTFQS HLNKALWKVG KLTSPGALLF Q
//
