ID A0A2K5V775_MACFA Unreviewed; 1280 AA.
AC A0A2K5V775;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cell adhesion associated, oncogene regulated {ECO:0000313|Ensembl:ENSMFAP00000020602.2};
GN Name=CDON {ECO:0000313|Ensembl:ENSMFAP00000020602.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000020602.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000020602.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000020602.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5V775; -.
DR STRING; 9541.ENSMFAP00000020602; -.
DR Ensembl; ENSMFAT00000035395.2; ENSMFAP00000020602.2; ENSMFAG00000033244.2.
DR VEuPathDB; HostDB:ENSMFAG00000033244; -.
DR GeneTree; ENSGT00940000157114; -.
DR OrthoDB; 3138076at2759; -.
DR Proteomes; UP000233100; Chromosome 14.
DR Bgee; ENSMFAG00000033244; Expressed in cerebellum and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF1; CELL ADHESION MOLECULE-RELATED_DOWN-REGULATED BY ONCOGENES; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 980..1005
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..178
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 241..319
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 326..412
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 421..532
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 595..693
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 739..834
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 842..942
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 949..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1251..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 954..968
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1280 AA; 137530 MW; 0B914F610057C652 CRC64;
MEGPVRIAAA ATVAAAARAG MTWGGFPSRL PRRRSGGLAS PAESEPRPGF CSGSLSCLLL
SSGAMHPELG ALCTLLYVTL TALCSSVSSD LAPYFTSEPL STVQKLGGPV VLHCSAKPGT
THISWLHNGK KLDGNMEHTK IHQGTLTILS LNSSLLGYYQ CLANNSIGAI VSGPATVSVA
VLGDFGSSTK HVITAEENSA GFIGCRVPES NPRAEVRYKI RGKWLKHSTG PSSDDFHILH
PTHSQALAVL SRSPVTLECV VSGVPAPPVY WLKDGQDIAP GSSWRRLYSH LATDSIDPAD
SGNYSCMVGN KSGDVKYVTY MVNVLEHASI SKGLQDQTVS LGATVHFTCD VRGNPAPNCT
WFHNAQPIHP SARRLTAGNG LKISGVTVED AGMYQCVADN GIGFMQSTGR LEIENDSGFK
PVIITAPASA KVADGGFVTL SCNASGMPVP VIRWYDSHGL ITSHPSQVLR SKSRKSQLSR
PEGLNLEPVY FVMSQAGASS LHIQAVTQEH AGRYICEATN EHGSTQAEAS LMVVPFETNT
KAETVTLPDA AQNDERNKRD GSETGLLSSF PVKVHPSAVE TAPEKNASGI SVPDAPIILS
PPQTHTPDTY NLLWRAGKDG GLPINAYFVK YRKLDDGVGM VGSWHTVRVP GSENELHLAE
LEPSSLYEVL MVARSAAGEG QPAMLTFRTS REKTASSKNT QASSPPVGIP KYPVVSEAAN
NNFGVVLTDS SRHSGVPEAP DRPTISTASE TSVYVTWIPR ANGGSPITAF KVEYKQMRTS
DWLVAAEDIP PSKLSVEVRS LEPGSTYKFR VIAINHYGES FRSSASRPYQ VAGFPSRFSN
RPVTGPHIAY TEAVSDTQIM LKWTYIPSSN NNTPIQGFYI YYRPTDSDND SDYKRDVVEG
SKQWHMIGHL QPETSYDIKM QCFNEGGESE FSNVMICETK VKRVPGASEY PVKDLSTPPN
SSGSGGNVGP AASPARSSDM LYLIVGCVLG VMVLILMVFI AMCLWKNRQQ NTIQKYDPPG
YLYQGSDMNG QMVEYTTLSG ASQINGNVHG GFLTNGGLSS GYSHLHRKVP NGVNGIVNGS
LNGGLYSGHN NSLTRTHVDF EHPHHLVNGG GMYTAVPQID PLECVNCRNC RNNNRCFTKT
NSTFSSSPLP VVPVVAPYPQ DGLEMKPLSH MKVPVCLASA VPDCGQLPEE SIKDNVEPVP
TQRTCCQDIV NDVSSDRAED PAEFSRGDSC AHSETENNIV SWNALISPPV PEGCAEKTTW
SPPGIPLDSP TEVLQQPQET
//
