ID A0A2K5V8S7_MACFA Unreviewed; 346 AA.
AC A0A2K5V8S7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Scratch family transcriptional repressor 1 {ECO:0000313|Ensembl:ENSMFAP00000021127.2};
GN Name=SCRT1 {ECO:0000313|Ensembl:ENSMFAP00000021127.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000021127.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000021127.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000021127.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5V8S7; -.
DR STRING; 9541.ENSMFAP00000021127; -.
DR Ensembl; ENSMFAT00000034875.2; ENSMFAP00000021127.2; ENSMFAG00000035496.2.
DR VEuPathDB; HostDB:ENSMFAG00000035496; -.
DR GeneTree; ENSGT00940000154491; -.
DR Proteomes; UP000233100; Chromosome 8.
DR Bgee; ENSMFAG00000035496; Expressed in cerebellum and 2 other cell types or tissues.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:2001222; P:regulation of neuron migration; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24388:SF60; TRANSCRIPTIONAL REPRESSOR SCRATCH 1; 1.
DR PANTHER; PTHR24388; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 189..216
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 246..273
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 274..301
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 302..320
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 136..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 35446 MW; 3EB03615D3353490 CRC64;
MPRSFLVKKV KLDAFSSADL ESAYGRARSD LGAPLHDKGY LSDYVGPSSV YDGDAEAALL
KGPSPEPMYA AAVRGELGPA AAGSAPPPTP RPELATAAGG YINGDAAVSE GYAADAFFIT
DGRSRRKASN ASSAAASTAS AAAPDGDAGG GGGAGGRSLG SGPGRGGTRA GAGTEARAGP
GAAGAGGRHA CGECGKTYAT SSNLSRHKQT HRSLDSQLAR RCPTCGKVYV SMPAMAMHLL
THDLRHKCGV CGKAFSRPWL LQGHMRSHTG EKPFGCAHCG KAFADRSNLR AHMQTHSAFK
HFQCKRCKKS FALKSYLNKH YESACFKGGA GGPAAPAPPQ LSPVQA
//
