ID   A0A2K5VAC1_MACFA        Unreviewed;       433 AA.
AC   A0A2K5VAC1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Divergent protein kinase domain 2B {ECO:0000313|Ensembl:ENSMFAP00000021694.2};
GN   Name=DIPK2B {ECO:0000313|Ensembl:ENSMFAP00000021694.2};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000021694.2, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000021694.2, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000021694.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the DIPK family.
CC       {ECO:0000256|ARBA:ARBA00006338}.
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DR   AlphaFoldDB; A0A2K5VAC1; -.
DR   STRING; 9541.ENSMFAP00000021694; -.
DR   Ensembl; ENSMFAT00000034323.2; ENSMFAP00000021694.2; ENSMFAG00000035756.2.
DR   VEuPathDB; HostDB:ENSMFAG00000035756; -.
DR   GeneTree; ENSGT00520000055625; -.
DR   OrthoDB; 2919302at2759; -.
DR   Proteomes; UP000233100; Chromosome X.
DR   Bgee; ENSMFAG00000035756; Expressed in heart and 6 other cell types or tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR020519; DIPK2A/B.
DR   InterPro; IPR022049; FAM69_kinase_dom.
DR   PANTHER; PTHR32073:SF8; DIVERGENT PROTEIN KINASE DOMAIN 2B; 1.
DR   PANTHER; PTHR32073; GH11358P; 1.
DR   Pfam; PF12260; PIP49_C; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..433
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030051401"
FT   DOMAIN          211..389
FT                   /note="FAM69 protein-kinase"
FT                   /evidence="ECO:0000259|Pfam:PF12260"
SQ   SEQUENCE   433 AA;  48504 MW;  5F393AB133E8929C CRC64;
     MEPQLGPEAA ALRPGWLALL LWVSALSCSF SLPASSPSSL VSQVRTSYNF GRTFLGLDKC
     NACIGTSICK KFFKEEIRSD NWLASHLGLS PNFLLSYPAN YSDDSKIWRP VEIFRLVSNY
     QNEISDRRIC ASASAPRTCS IERVLRKTER FQKWLQAKRL TPDLVQGLAS PLLRCPSQRL
     LDRVVRRYAE VADAGSIFMD HFTDRDKLRL LYTLAVNSHP ILLQIFPGAE GWPLPQYLGS
     CGRFLVSTST RPLQEFYGAP PDQAADLAYQ LLSVLESLRS NDLNYFFYFT HIDAGMFGVF
     NNGHLFIRDA GAVGVIDKQE GSQEATRAGE NKDIFSCLVS GCQAQLPSCE SVSEKQSLVL
     VCQKLLPRLL QGRFPSPVQD DIDSALAQCG DSTRPDPEVL GAASWLKHIL RPLRTCDSRF
     AYRYPDCKYN DKF
//