ID A0A2K5VDF9_MACFA Unreviewed; 1458 AA.
AC A0A2K5VDF9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=CD163 molecule like 1 {ECO:0000313|Ensembl:ENSMFAP00000022741.2};
GN Name=CD163L1 {ECO:0000313|Ensembl:ENSMFAP00000022741.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000022741.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000022741.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000022741.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR STRING; 9541.ENSMFAP00000022741; -.
DR Ensembl; ENSMFAT00000030871.2; ENSMFAP00000022741.2; ENSMFAG00000043061.2.
DR VEuPathDB; HostDB:ENSMFAG00000043061; -.
DR GeneTree; ENSGT00940000164229; -.
DR OrthoDB; 5403281at2759; -.
DR Proteomes; UP000233100; Chromosome 11.
DR Bgee; ENSMFAG00000043061; Expressed in colon and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 12.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 12.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 12.
DR SUPFAM; SSF56487; SRCR-like; 12.
DR PROSITE; PS00420; SRCR_1; 5.
DR PROSITE; PS50287; SRCR_2; 12.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1366..1388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..148
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 165..265
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 272..372
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 379..479
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 486..586
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 593..693
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 700..800
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 800..900
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 905..1005
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1041..1141
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1146..1248
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1251..1351
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 1423..1445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1423..1444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 73..137
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 86..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 117..127
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 190..254
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 203..264
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 234..244
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 297..361
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 310..371
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 341..351
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 404..468
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 417..478
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 448..458
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 511..575
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 524..585
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 555..565
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 618..682
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 631..692
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 662..672
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 725..789
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 738..799
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 769..779
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 825..889
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 838..899
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 869..879
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 930..994
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 943..1004
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 974..984
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1066..1130
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1079..1140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1110..1120
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1186..1247
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1217..1227
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1276..1340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1289..1350
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1320..1330
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1458 AA; 159564 MW; A3A31BB9D623EFD3 CRC64;
MMLPQNSWHI DLGRCCCHQN LFSAMVTCIL LLNSCFLISS FNGTDLELRL VDGDGPCSGR
VEVKFQGQWG TVCDDGWNPA ASIVVCKQLG CPFSFTMFHF GQAVTRYGKI WLDDVSCYGN
ESALWECQHR EWGSHDCNHG EDVGVNCYGK SLTRVGRQGE ANLGLRLVDG NSSCSGRVEV
KFQERWGTIC DDGWNSNTAA VVCRQLGCPS SFISSGVVDS PAVLGPIWLD DIICQGNELA
IWNCRHRGWG NHDCSHYEDV TLTCYDSSDL ELRLVGGTNR CVGRVELKIQ GRWGTICHHK
WNNAAADVVC KQLGCGTALH FAGLPHLQSG SDVVWLDGVS CSGNESFLWD CRHSATVNMD
CIHQNDVSVI CSDGADLELR LADGSDNCSG RVEVRIHEQW WTICDQNWKN EQALVVCKQL
GCPFSVFGSR RAKPSNEARD IWINSISCTG NESSLWDCIY DGKAKRTCFR RSDAGVICSD
KADLDLRLAG ADSPCYGRLE VKYQGQWGTV CHDRWSTRNA AVVCKRLGCG KPIRMFGITY
FKEASGPIWL DDVSCIGNES DIWDCKHNGW GKHNCVHRED VIVTCSGNAT WGLRLAGGSN
RCSGRLEVYF QEQWGTVCDD GWNSIAAAVV CSQLDCPTSI IGMGLGNTST GYGKIWLDDV
SCDGDESDLW SCRNSGWGNN DCSHGEDVGV ICSDASDMEL RLVGGSSRCA GRVEVKVQGA
SGILCANSWG INIAEVVCRQ LECGSPILVY REPHFTERTL HIFISNSGCT GREASLWDCI
RWEWKQTACR LNMEASVICS RLVGADMPCS GRVEVKRADT WGSVCDSDFS LHAASVLCRE
LNCGDAVSLS VGDHFGKGSG LTWAEKIQCE GSETHLALCP TVQHPEDTCI HSREVGVVCS
RYTDVRLVNG KSQCDGQVEI KVLGQWGLLC DTHWYPEDAH VLCRQLSCGA AVSTTGGKYI
GERTGRVWGH RFHCLGNESL LDNCQMTVLG APPCIHGNTV SVICTGSLTG PLLPCVANLS
DPYLSAVPEG RAFICLEDKR LRLVNGDGRC AGRVEIYHNG MWGTICDDGW DLSDAHVVCR
KLGCGVALNA TVSAHFGAGS GPIWLDDLNC IGTESHLWQC PSRGWGQHDC RHKEDAGVIC
SEFTALRLYS ETEVESCAGR LEVFYNGTWG SVGRRNITTA IAGIVCKQLG CGENGVVSLA
PLSKIGSGFM WVDDIQCSKT HISIWQCLSA PWERRISSPA EETWITCEDR IRVRGGDTEC
SGRVEIWHAG SWGTVCDDSW DLAEAEVVCQ QLGCGSALAA LKEASFGQGT GTIWLDEMQC
KGNESFLWDC HAKPWGQSDC GHKEDAGVRC SGQSLKSPNA SSGHSALILS SIFGLLLLVL
FILFLTWCQV QKQKHLSLRV STRRRGSLEE NLFQEMETCL KREDPHGTRT SDDTPSHGCE
DARDTSLLEV LPASEATK
//
