ID A0A2K5VEK2_MACFA Unreviewed; 461 AA.
AC A0A2K5VEK2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN Name=POLK {ECO:0000313|Ensembl:ENSMFAP00000023137.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000023137.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000023137.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000023137.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5VEK2; -.
DR Ensembl; ENSMFAT00000031271.2; ENSMFAP00000023137.2; ENSMFAG00000043179.2.
DR VEuPathDB; HostDB:ENSMFAG00000043179; -.
DR GeneTree; ENSGT00940000156667; -.
DR Proteomes; UP000233100; Chromosome 6.
DR Bgee; ENSMFAG00000043179; Expressed in lung and 13 other cell types or tissues.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR Gene3D; 1.10.150.810; -; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR022880; DNApol_IV.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 103..358
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT COILED 57..99
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 461 AA; 52722 MW; 966A604EC77E1CD7 CRC64;
MDSIKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV
NQRIENMMQQ KAEITSQQLR KAQLQVDRFA MELEQSRNLS NTIVHIDMDA FYAAVEMRDN
PELKDKPIAV GSMSMLSTSN YHARRFGVRA AMPGFIAKRL CPQLIIVPPN FDKYRAVSKE
VKEILADYDP NFMAMSLDEA YLNITKHLEE RQNWPEDKRK YFIKMGNSVE NDNPGKEVNK
LSDHERSISP LLFEASPSDL LPPGDPFQVN FEEQNSPQIL QNSIVFGTSA EEVVKEIRFR
IEQKTTLTAS AGIAPNTMLA KVCSDKNKPN GQYQILPNRQ AVMDFIKDLP IRKVSGIGKV
TEKMLKALGI ITCTELYQQR ALLSLLFSET SWHYFLHISL GLGSTYLTRD GERKSMSVER
TFSEINKAEE QYSLCEELCS ELARDLQKEG LKVAQVEYRR L
//
