ID A0A2K5VFJ1_MACFA Unreviewed; 840 AA.
AC A0A2K5VFJ1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=EMAP like 1 {ECO:0000313|Ensembl:ENSMFAP00000023480.2};
GN Name=EML1 {ECO:0000313|Ensembl:ENSMFAP00000023480.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000023480.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000023480.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000023480.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005562245.1; XM_005562188.2.
DR AlphaFoldDB; A0A2K5VFJ1; -.
DR SMR; A0A2K5VFJ1; -.
DR Ensembl; ENSMFAT00000031614.2; ENSMFAP00000023480.2; ENSMFAG00000043375.2.
DR GeneID; 102140961; -.
DR KEGG; mcf:102140961; -.
DR CTD; 2009; -.
DR VEuPathDB; HostDB:ENSMFAG00000043375; -.
DR GeneTree; ENSGT00940000153887; -.
DR Proteomes; UP000233100; Chromosome 7.
DR Bgee; ENSMFAG00000043375; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR CDD; cd21947; TD_EMAP1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF22; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 213..284
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 564..596
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 693..724
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 805..840
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 840 AA; 92376 MW; 1318C3CF32088191 CRC64;
MSDGEGPSAD DSASAASSME VTDRIASLEQ RVQMQEDDIQ LLKSALADVV RRLNITEEQQ
AVLNRKGPTK ARPLMQTLPL RTTVNNGTVL PKKSSGSLPS PSGARKETAV PTTKRLNRSV
SLLNACKLNR STPSNIKRTS SSERVSPGGR RESNGDSKGN RNRTGSTSSS SSGKKNSESK
PKEPVFSAAL LSLSPKSQGK RRVTHCKEEG YVKMFLRGRP VTMYMPKDQV DSYSLEAKVE
LPTKRLKLEW VYGYRGRDCR NNLYLLPTGE TVYFIASVVV LYNVEEQLQR HYAGHNDDVK
CLAVHPDRIT IATGQVAGTS KDGKQLPPHV RIWDSVTLNT LHVIGIGFFD RAVTCIAFSK
SNGGTNLCAV DDSNDHVLSV WDWQKEEKLA DVKCSNEAVF AADFHPTDTN IIVTCGKSHL
YFWTLEGSSL NKKQGLFEKQ EKPKFVLCVT FSENGDTITG DSSGNILVWG KGTNRISYAV
QGAHEGGIFA LCMLRDGTLV SGGGKDRKLI SWSGNYQKLR KTEIPEQFGP IRTVAEGKGD
VILIGTTRNF VLQGTLSGDF TPITQGHTDE LWGLAIHASK PQFLTCGHDK HATLWDAVGH
RPVWDKIIED PAQSSGFHPS GSVVAVGTLT GRWFVFDTET KDLVTVHTDG NEQLSVMRYS
PDGNFLAIGS HDNCIYIYGV SDNGRKYTRV GKCSGHSSFI THLDWSVNSQ FLVSNSGDYE
ILYWVPSACK QVVSVETTRD IEWATYTCTL GFHVFGVWPE GSDGTDINAV SRAHEKKLLS
TGDDFGKVHL FSYPCSQFRA PSHIYGGHSS HVTNVDFLCE DSHLISTGGK DTSIMQWRVI
//
