ID A0A2K5VQB0_MACFA Unreviewed; 571 AA.
AC A0A2K5VQB0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Double-stranded RNA-binding protein Staufen homolog 2 {ECO:0000256|ARBA:ARBA00024122};
GN Name=STAU2 {ECO:0000313|Ensembl:ENSMFAP00000026916.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000026916.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000026916.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000026916.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5VQB0; -.
DR Ensembl; ENSMFAT00000001098.2; ENSMFAP00000026916.2; ENSMFAG00000044834.2.
DR VEuPathDB; HostDB:ENSMFAG00000044834; -.
DR GeneTree; ENSGT00940000154977; -.
DR Proteomes; UP000233100; Chromosome 8.
DR Bgee; ENSMFAG00000044834; Expressed in temporal lobe and 13 other cell types or tissues.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19882; DSRM_STAU2_rpt2; 1.
DR CDD; cd19884; DSRM_STAU2_rpt3; 1.
DR CDD; cd19886; DSRM_STAU2_rpt4; 1.
DR CDD; cd19888; DSRM_STAU2_rpt5; 1.
DR Gene3D; 3.30.160.20; -; 5.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR044464; STAU2_DSRM_2.
DR InterPro; IPR044473; STAU2_DSRM_3.
DR InterPro; IPR044474; STAU2_DSRM_4.
DR InterPro; IPR032478; Staufen_C.
DR PANTHER; PTHR46054:SF1; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2; 1.
DR PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR Pfam; PF00035; dsrm; 3.
DR Pfam; PF16482; Staufen_C; 1.
DR SMART; SM00358; DSRM; 3.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 4.
DR PROSITE; PS50137; DS_RBD; 3.
PE 4: Predicted;
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 58..144
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 170..237
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 270..338
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 62524 MW; A29A40764BB53C42 CRC64;
MMFSVQLSLG EQTWESEGSS IKKAQQAVAN KALTESTLPK PVQKPPKSNV NNNPGSITPT
VELNGLAMKR GEPAIYRPLD PKPFPNYRAN YNFRGMYNQR YHCPVPKIFY VQLTVGNNEF
FGEGKTRQAA RHNAAMKALQ ALQNEPIPER SPQNGESGKD MDDDKDANKS EISLVFEIAL
KRNMPVSFEV IKESGPPHMK SFVTRVSVGE FSAEGEGNSK KLSKKRAATT VLQELKKLPP
LPVVEKPKLF FKKRPKTIVK AGPEYGQGMN PISRLAQIQQ AKKEKEPDYV LLSERGMPRR
REFVMQVKVG SEVATGTGPN KKIAKKNAAE AMLLQLGYKA STNLQDQLEK TGENKGWSGP
KPGFPEPTNN TPKGILHLSP DVYQEMEASR HKVISGTTLG YLSPKDMNQP SSSFFSISPT
SNSSATIARE LLMNGTSSTA EAIGLKGSSP TPPCSPVQPS KQLEYLARIQ GFQVHYCDRQ
SGKECVTCLT LAPVQMTFHA IGSSIEASHD QAALSALKQF SEQGLDPIDG AMNIEKGSLE
KQAKHLREKA DNNQAPPGSI AQDCKKSNSA V
//
