ID A0A2K5VW30_MACFA Unreviewed; 340 AA.
AC A0A2K5VW30;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=GTPase, IMAP family member 2 {ECO:0000313|Ensembl:ENSMFAP00000028993.2};
GN Name=GIMAP2 {ECO:0000313|Ensembl:ENSMFAP00000028993.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000028993.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000028993.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000028993.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K5VW30; -.
DR STRING; 9541.ENSMFAP00000028993; -.
DR Ensembl; ENSMFAT00000003185.2; ENSMFAP00000028993.2; ENSMFAG00000041785.2.
DR VEuPathDB; HostDB:ENSMFAG00000041785; -.
DR GeneTree; ENSGT00940000163457; -.
DR OrthoDB; 938643at2759; -.
DR Proteomes; UP000233100; Chromosome 3.
DR Bgee; ENSMFAG00000041785; Expressed in lymph node and 8 other cell types or tissues.
DR GO; GO:0005811; C:lipid droplet; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF7; GTPASE IMAP FAMILY MEMBER 2; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 283..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..223
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
SQ SEQUENCE 340 AA; 38510 MW; C705CC15A54EF6B4 CRC64;
MDQNEHNHWG SHAKGQCASR SELRIILVGK TGTGKSAAGN SILRKQAFES KLSSWTLTKT
CSKSQGSWGD REIVIIDTPD MLSWKDHCEA LYKEVQRCYL LSAPGPHVLL LVTQLGRYTS
QDQEAAQRVK EIFGEDAMRH TIVLFTHKED LSGGSLMDYM RNSDNKALSK LVAACGGRIC
AFNNRAEGRN QDDQVKELMD LIEDLLMEKN GDHYTNGLYS LIQRSKCGSV GSDQKLKEFK
ESLIKYMETQ RSYTALAEAN CLKRALIKTQ LCVLFCIQLC LRLLILLLCI LHSMCTLFCC
LLFSMCNLLC SLLFIIPKKL MIVSRTVIRL ERRTPRLFTH
//
